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    Figure 4个  Table 3个
    • Country Abbreviation Year References
      Africa
      Burkina Faso* BF 1981 Faye et al., 2014
      Cape Verde CV 2015 Kindhauser et al., 2016
      http://www.cdc.gov/zika/geo/active-countries.html
      Central African Republic* CF 1968, 1976, 1979, 1980 Saluzzo et al., 1981; Berthet et al., 2014
      Cote d'Ivoire* CI 1980–1996, 1999 Faye et al., 2014
      Egypt EG 1954 Smithburn et al., 1954
      Gabon* GA 1975, 2007 Jan et al., 1978; Grard et al., 2014
      Nigeria* NG 1953, 1964–1970 Macnamara, 1954; Moore et al., 1975; Kindhauser et al., 2016
      Senegal* SN 1960s–1970s, 1990s–2000s Faye et al., 2014; Kindhauser et al., 2016
      Tanzania TZ 1952 Smithburn, 1952
      Uganda * UG 1947, 1952, 1963 Dick et al., 1952; Smithburn, 1952; Faye et al., 2014
      Americas
      Barbados BB 2016 http://www.who.int/csr/don/20-january-2016-zika-guyanabarbados-ecuador/en/
      Bolivia BO 2016 http://www.who.int/csr/don/20-january-2016-zika-bolivia/en/
      Brazil* BR 2015 Waggoner and Pinsky, 2016
      http://www.who.int/csr/don/21-october-2015-zika/en/
      Canada§* CA 2014, 2016 Fonseca et al., 2014 http://www.phac-aspc.gc.ca/phn-asp/2016/zika-eng.php
      Chile mainland § CL 2016 Kindhauser et al., 2016
      Colombia CO 2015 Enserink, 2015; Kindhauser et al., 2016
      http://www.who.int/csr/don/21-october-2015-zika/en/
      Commonwealth of Puerto Rico PR 2015 http://www.who.int/csr/don/8-january-2016-zika-usa/en/
      Costa Rica CR 2016 http://www.who.int/csr/don/8-february-2016-zika-americas-region/en/
      Curacao
      (Netherlands Antilles)§
      Curacao(AN) 2016 http://www.who.int/csr/don/8-february-2016-zika-americas-region/en/
      Dominican Republic§ DO 2016 http://www.who.int/csr/don/27-january-2016-zika-dominican-republic/en/
      Easter Island (Chile)* Easter Island (CL) 2014 Tognarelli et al., 2015
      Ecuador§ EC 2016 http://www.who.int/csr/don/20-january-2016-zika-guyana-barbados-ecuador/en/
      El Salvador SV 2015 http://www.who.int/csr/don/27-november-2015-zika-el-salvador/en/
      French Guiana and Martinique(France) GF and MQ 2015 http://www.who.int/csr/don/8-january-2016-zika-france/en/
      Guatemala GT 2015 http://www.who.int/csr/don/27-november-2015-zika-guatemala/en/
      Guyana GY 2016 http://www.who.int/csr/don/20-january-2016-zika-guyana-barbados-ecuador/en/
      Haiti HT 2016 http://www.who.int/csr/don/21-january-2016-zika-haiti/en/
      Honduras HN 2015 http://www.who.int/csr/don/21-december-2015-zika-honduras/en/
      Jamaica§ JM 2016 http://www.who.int/csr/don/8-february-2016-zika-americas-region/en/
      Mexico* MX 2015-2016 http://www.who.int/csr/don/03-december-2015-zika-mexico/en/
      Nicaragua NI 2016 http://www.who.int/csr/don/8-february-2016-zika-americas-region/en/
      Panama PA 2015 http://www.who.int/csr/don/22-december-2015-zika-panama/en/
      Paraguay PY 2015 http://www.who.int/csr/don/03-december-2015-zika-paraguay/en/
      Saint Martin and Guadeloupe(France) Saint Martin and GP 2016 http://www.who.int/csr/don/21-january-2016-zika-france/en/
      Suriname* SR 2015 Enfissi et al., 2016a
      http://www.who.int/csr/don/13-november-2015-zika/en/
      United States of America§ US 2007–2016 Duffy et al., 2009; Foy et al., 2011
      http://www.who.int/csr/don/12-february-2016-zika-usa/en/; http://www.who.int/csr/don/12-february-2016-microcephaly-usa/en/
      United States Virgin Islands VI(US) 2016 http://www.who.int/csr/don/29-january-2016-zika-usa/en/
      Venezuela VE 2015 http://www.who.int/csr/don/03-december-2015-zika-venezuela/en/
      Asia
      Cambodia* KH 2010 Heang et al., 2012
      Guangdong(China)§ Guangdong(CN) 2016 http://www.nhfpc.gov.cn
      India IN N/A† Kindhauser et al., 2016
      Indonesia ID 1977, 1981, 2012 Olson et al., 1981; Olson et al., 1983; Kindhauser et al., 2016
      Israel§ IL 2016 http://www.haaretz.com/israel-news/.premium-1.698798
      Malaysia* MY 1966 Pond, 1963; Marchette et al., 1969; Kindhauser et al., 2016
      Pakistan PK 1983 Darwish et al., 1983
      Philippines* PH 2012 Alera et al., 2015
      Taiwan(China)§ Taiwan(CN) 2016 www.cdc.gov.tw
      Thail and * TH 2012-2014 Pond, 1963; Buathong et al., 2015; Kindhauser et al., 2016
      Vietnam VN N/A‡ Pond, 1963
      Europe
      Austria§ AT 2016 http://www.thelocal.at/20160128/first-confirmed-case-of-zika-virus-in-austria
      Denmark§ DK 2016 http://time.com/4195372/zika-denmark-south-america-europe/
      Finl and § FI 2015 http://www.who.int/csr/don/8-february-2016-zika-maldives/en/
      Germany§ DE 2014, 2016 Tappe et al., 2015
      http://www.who.int/csr/don/21-january-2016-zika-haiti/en/
      Italy§ IT 2015 Zammarchi et al., 2015
      Netherl and s§ NL 2016 http://www.who.int/csr/don/22-february-2016-zika-netherlands/en/
      Norway§* NO 2013 Waehre et al., 2014
      Portugal§ PT 1972 Filipe et al., 1973
      Spain§ ES 2016 http://elpais.com/elpais/2016/02/02/inenglish/1454423888_908441.html
      Sweden§ SE 2016 http://sputniknews.com/europe/20160127/1033787120/zika-virus-sweden-case.html
      Switzerl and § CH 2016 http://www.thelocal.ch/20160126/two-zika-virus-cases-reported-in-switzerland
      United Kingdom§ UK 2016 http://www.techtimes.com/articles/127390/20160125/uk-confirms-three-new-cases-of-mosquito-borne-zika-virus.htm
      Oceania
      American Samoa AS 2015 http://www.nc.cdc.gov/travel/notices/alert/zika-virus-pacific-islands
      Australia§ AU 2015 Leung et al., 2015
      Cook Islands* CK 2014 Roth et al., 2014
      Fiji FJ 2015 Kindhauser et al., 2016
      French Polynesia* PF 2013 Baronti et al., 2014; Cao-Lormeau et al., 2014; Hancock et al., 2014
      Marshall Islands MH 2015 http://www.nc.cdc.gov/travel/notices/alert/zika-virus-pacific-islands
      New Caledonia*§ NC 2013, 2014 Roth et al., 2014; Dupont-Rouzeyrol et al., 2015
      Samoa WS 2015, 2016 Kindhauser et al., 2016
      http://www.nc.cdc.gov/travel/notices/alert/zika-virus-pacific-islands
      Solomon Islands SB 2015 Kindhauser et al., 2016
      Tonga TO 2015 http://www.nc.cdc.gov/travel/notices/alert/zika-virus-pacific-islands
      Vanuatu VU 2015 Kindhauser et al., 2016
      Yap Island (Micronesia) Yap Island (FM) 2007 Lanciotti et al., 2008; Duffy et al., 2009
      §Countries and territories where the imported cases were reported.
      *Countries and territories where the complete or partial ZIKV sequences were identified and deposited in GenBank.
      †The year that ZIKV was detected in India is uncertain. It was only mentioned by a WHO research article found online(Kindhauser et al., 2016)that during 1969–1983 the geographic distribution of ZIKV expanded to equatorial Asian countries, including India, Indonesia, Malaysia, and Pakistan.
      ‡The year that ZIKV was detected in Vietnam is uncertain. The previous study(Pond, 1963)investigated the serological prevalence of antibodies against ZIKV among the population in Vietnam before 1963.

      Table 1.  Summary of the countries and territories with a history of ZIKV disease and reported cases

    • Event
      No.
      Recombinants
      (location/time/lineage)
      Major parents
      (location/time/lineage)
      Minor parents
      (location/time/lineage)
      Methods RDPRCS Begin End
      1 ArD157995
      Senegal/2001/A1
      ArA975 Cote
      d'Ivoire/1999/A1
      ArD132915
      Senegal/1998/A2
      GENECONV, MaxChi, RDP, SiScan, 3Seq, Chimaera 0.682 9754 10314
      2 ArA1456 Cote
      d'Ivoire/1980/A1
      ArD30101
      Senegal/1979/A1
      ArD132915
      Senegal/1998/A2
      SiScan, 3Seq, Chimaera 0.594 9672 10315
      3 ArD158084
      Senegal/2001/A1
      ArB15076 Central African
      Republic/1980/A1
      ArD157995
      Senegal/2001/A1
      3Seq, MaxChi 0.685 9672 10315
      Note: A1, African lineage 1; A2, African lineage 2.

      Table 2.  The recombination events of ZIKV detected by the RDP software package

    • Strains Locations Time Lineages
      Full-length E gene NS5 gene
      ArD157995 Senegal 2001 A1 A1 A1
      ArA1465 Cote d'Ivoire 1980 N/A A2 A1
      Notes: A1, African lineage 1; A2, African lineage 2; N/A, not applicable.

      Table Table S1.  Strains of discrepancies among tree topology by visual comparison