• Agarwal R, Chang J, Cortes FH, et al. Chikungunya virus-specific CD4(+) T cells are associated with chronic chikungunya viral arthritic disease in humans. Cell Rep Med. 2025. 6(5): 102134.

  • Azar SR, Campos RK, Bergren NA, Camargos VN, Rossi SL. Epidemic Alphaviruses: Ecology, Emergence and Outbreaks. Microorganisms. 2020. 8(8): 1167.

  • Baloch Z, Shen Z, Zhang L, et al. Recapitulating Zika Virus Infection in Vagina of Tree Shrew (Tupaia belangeri). Front Cell Infect Microbiol. 2021. 11: 687338.

  • Borgherini G, Poubeau P, Staikowsky F, et al. Outbreak of chikungunya on Reunion Island: early clinical and laboratory features in 157 adult patients. Clin Infect Dis. 2007. 44(11): 1401-1407.

  • Chan, Y.H., Lum, F.M. and Ng, L., 2015. Limitations of Current in Vivo Mouse Models for the Study of Chikungunya Virus Pathogenesis. Medical sciences (Basel, Switzerland) 3, 64-77.

  • Couderc, T., Chretien, F., Schilte, C., Disson, O., Brigitte, M., Guivel-Benhassine, F., Touret, Y., Barau, G., Cayet, N., Schuffenecker, I., Despres, P., Arenzana-Seisdedos, F., Michault, A., Albert, M.L. and Lecuit, M., 2008. A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease. PLoS pathogens 4, e29.

  • Cunningham A, Buckley SM, Casals J, Webb SR. Isolation of chikungunya virus contaminating an Aedes albopictus cell line. J Gen Virol. 1975. 27(1): 97-100.

  • Ding L, Fan L, Xu X, Fu J, Xue Y. Identification of core genes and pathways in type 2 diabetes mellitus by bioinformatics analysis. Mol Med Rep. 2019. 20(3): 2597-2608.

  • Dupuis-Maguiraga L, Noret M, Brun S, Le Grand R, Gras G, Roques P. Chikungunya disease: infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia. PLoS Negl Trop Dis. 2012. 6(3): e1446.

  • Fritzer A, Suhrbier A, Hugo LE, et al. Assessment of the transmission of live-attenuated chikungunya virus vaccine VLA1553 by Aedes albopictus mosquitoes. Parasit Vectors. 2025. 18(1): 171.

  • Gardner, J., Anraku, I., Le, T.T., Larcher, T., Major, L., Roques, P., Schroder, W.A., Higgs, S. and Suhrbier, A., 2010. Chikungunya virus arthritis in adult wild-type mice. Journal of virology 84, 8021-8032.

  • Geng T, Lin T, Yang D, et al. A Critical Role for STING Signaling in Limiting Pathogenesis of Chikungunya Virus. J Infect Dis. 2021. 223(12): 2186-2196.

  • Goupil BA, McNulty MA, Martin MJ, McCracken MK, Christofferson RC, Mores CN. Novel Lesions of Bones and Joints Associated with Chikungunya Virus Infection in Two Mouse Models of Disease: New Insights into Disease Pathogenesis. PLoS One. 2016. 11(5): e0155243.

  • Guerrero-Arguero I, Hoej TR, Tass ES, Berges BK, Robison RA. A comparison of Chikungunya virus infection, progression, and cytokine profiles in human PMA-differentiated U937 and murine RAW264.7 monocyte derived macrophages. PLoS One. 2020. 15(3): e0230328.

  • Guinn KM, Rubin EJ. Tuberculosis: Just the FAQs. mBio. 2017. 8(6): e01910-17.

  • Haese, N.N., Broeckel, R.M., Hawman, D.W., Heise, M.T., Morrison, T.E. and Streblow, D.N., 2016. Animal Models of Chikungunya Virus Infection and Disease. The Journal of infectious diseases 214, S482-S487.

  • Hallengard, D., Kakoulidou, M., Lulla, A., Kummerer, B.M., Johansson, D.X., Mutso, M., Lulla, V., Fazakerley, J.K., Roques, P., Le Grand, R., Merits, A. and Liljestrom, P., 2014. Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice. Journal of virology 88, 2858-2866.

  • Huang Z, Shi N, Luo Z, et al. Identification and characterization of the tumor necrosis factor receptor superfamily in the Chinese tree shrew (Tupaia belangeri chinensis). BMC Genomics. 2025. 26(1): 338.

  • Johnson B, VanBlargan LA, Xu W, et al. Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability. Immunity. 2018. 48(3): 487-499.e5.

  • Karim SU, Nazneen F, Denyoh P, Bai DS, Romero DG, Bai F. Heterozygous interferon signaling deficient mice as animal models for Chikungunya virus infection in the heart. Sci Rep. 2025. 15(1): 18022.

  • Kayesh M, Sanada T, Kohara M, Tsukiyama-Kohara K. Tree Shrew as an Emerging Small Animal Model for Human Viral Infection: A Recent Overview. Viruses. 2021. 13(8): 1641.

  • Kramer IM, Pfeiffer M, Steffens O, et al. The ecophysiological plasticity of Aedes aegypti and Aedes albopictus concerning overwintering in cooler ecoregions is driven by local climate and acclimation capacity. Sci Total Environ. 2021. 778: 146128.

  • Krutikov M, Manson J. Chikungunya Virus Infection: An Update on Joint Manifestations and Management. Rambam Maimonides Med J. 2016. 7(4): e0033.

  • Labadie K, Larcher T, Joubert C, et al. Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages. J Clin Invest. 2010. 120(3): 894-906.

  • Lemaitre J, Naninck T, Delache B, et al. Non-human primate models of human respiratory infections. Mol Immunol. 2021. 135: 147-164.

  • Li XF, Dong HL, Huang XY, et al. Characterization of a 2016 Clinical Isolate of Zika Virus in Non-human Primates. EBioMedicine. 2016. 12: 170-177.

  • Liang X, Zhou Y, Yang Y, et al. CHIKV mRNA vaccines encoding conserved structural/envelope proteins confer broad cross-lineage protection against infection. Signal Transduct Target Ther. 2025. 10(1): 98.

  • Lin T, Geng T, Harrison AG, et al. CXCL10 Signaling Contributes to the Pathogenesis of Arthritogenic Alphaviruses. Viruses. 2020. 12(11): 1252.

  • Liu Y, Xu M, Xia B, et al. Nifuroxazide Prevents Chikungunya Virus Infection Both In Vitro and In Vivo via Suppressing Viral Replication. Viruses. 2024;16(8):1322.

  • Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014. 15(12): 550.

  • Lu, J.S., Yue, F., Liu, X., Chen, T. and Zhuo, M., 2016. Characterization of the anterior cingulate cortex in adult tree shrew. Molecular pain 12, 1744806916684515.

  • MASON PJ, HADDOW AJ. An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-1953; an additional note on Chikungunya virus isolations and serum antibodies. Trans R Soc Trop Med Hyg. 1957. 51(3): 238-240.

  • Morrison TE, Oko L, Montgomery SA, et al. A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence. Am J Pathol. 2011. 178(1): 32-40.

  • Ngwe Tun MM, Mutua MM, Inoue S, et al. Molecular and serological evidence of chikungunya virus among dengue suspected patients in Sri Lanka. J Infect Public Health. 2025. 18(5): 102709.

  • Ozden S, Huerre M, Riviere JP, et al. Human muscle satellite cells as targets of Chikungunya virus infection. PLoS One. 2007. 2(6): e527.

  • Pathak H, Mohan MC, Ravindran V. Chikungunya arthritis. Clin Med (Lond). 2019. 19(5): 381-385.

  • Phillips KA, Bales KL, Capitanio JP, et al. Why primate models matter. Am J Primatol. 2014. 76(9): 801-827.

  • Qi Y, Li Y, Zhang Y, et al. IFI6 Inhibits Apoptosis via Mitochondrial-Dependent Pathway in Dengue Virus 2 Infected Vascular Endothelial Cells. PLoS One. 2015. 10(8): e0132743.

  • Rama K, de Roo AM, Louwsma T, et al. Clinical outcomes of chikungunya: A systematic literature review and meta-analysis. PLoS Negl Trop Dis. 2024. 18(6): e0012254.

  • Sharma KB, Subramani C, Ganesh K, et al. Withaferin A inhibits Chikungunya virus nsP2 protease and shows antiviral activity in the cell culture and mouse model of virus infection. PLoS Pathog. 2024. 20(12): e1012816.

  • Simon F, Parola P, Grandadam M, et al. Chikungunya infection: an emerging rheumatism among travelers returned from Indian Ocean islands. Report of 47 cases. Medicine (Baltimore). 2007. 86(3): 123-137.

  • Tang WW, Young MP, Mamidi A, Regla-Nava JA, Kim K, Shresta S. A Mouse Model of Zika Virus Sexual Transmission and Vaginal Viral Replication. Cell Rep. 2016. 17(12): 3091-3098.

  • Taylor M, Rayner JO. Immune Response to Chikungunya Virus: Sex as a Biological Variable and Implications for Natural Delivery via the Mosquito. Viruses. 2023. 15(9): 1869.

  • Tjaden NB, Suk JE, Fischer D, Thomas SM, Beierkuhnlein C, Semenza JC. Modelling the effects of global climate change on Chikungunya transmission in the 21(st) century. Sci Rep. 2017. 7(1): 3813.

  • Traverse EM, Millsapps EM, Underwood EC, Hopkins HK, Young M, Barr KL. Chikungunya Immunopathology as It Presents in Different Organ Systems. Viruses. 2022. 14(8): 1786.

  • Tsetsarkin KA, Vanlandingham DL, McGee CE, Higgs S. A single mutation in chikungunya virus affects vector specificity and epidemic potential. PLoS Pathog. 2007. 3(12): e201.

  • Wan S, Zhang X, Cong X, et al. Viral Load Dynamics of Chikungunya Virus in Human Specimens - Foshan City, Guangdong Province, China, 2025. China CDC Wkly. 2025. 7(33): 1067-1072.

  • Werneke SW, Schilte C, Rohatgi A, et al. ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation. PLoS Pathog. 2011. 7(10): e1002322.

  • Yao YG, Lu L, Ni RJ, et al. Study of tree shrew biology and models: A booming and prosperous field for biomedical research. Zool Res. 2024. 45(4): 877-909.

  • Yauch LE, Shresta S. Mouse models of dengue virus infection and disease. Antiviral Res. 2008. 80(2): 87-93.

  • Zhang NN, Zhang L, Deng YQ, et al. Zika Virus Infection in Tupaia belangeri Causes Dermatological Manifestations and Confers Protection against Secondary Infection. J Virol. 2019. 93(8): e01982-18.

  • Zhang Y, Zhu J, Hu K, Qiu J, Zhang F. Multi-omics analyses construct an inflammatory response based prognostic gene signature for cervical cancer and suggest tumor infiltrating monocytes subgroups as key players. Front Immunol. 2025. 16: 1563593.

  • Zhou H, Tian RR, Wang XR, et al. Identification of novel mammalian viruses in tree shrews ( Tupaia belangeri chinensis). Zool Res. 2024. 45(2): 429-438.