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Groups No. tested Virus infection positive No. (%)a Single virus infection No. (%)b Co-infection No. (%)c Two viruses Three viruses Four viruses Five viruses Asthma 147 145 (98.6) 74 (50.3) 57 (38.8) 11 (7.5) 2 (1.4) 1 (0.7) Control 81 67 (82.7) 44 (54.3) 19 (23.5) 2 (2.5) 1 (1.2) 1(1.2) Note: a:χ2 = 17.9264, P < 0.05; b:χ2 = 0.1912, P > 0.05; c:χ2 = 7.7371, P < 0.05. Table 1. Viral screening results in different groups using the RVP FAST assay
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Viral type Asthma group (n = 147) Control group (n = 81) Total No. (%) Single No. (%a) Co-infected No. (%b) Total No. (%) Single No. (%a) Co-infected No. (%b) EV/HRV 113 (76.9) 55 (48.7) 58 (51.3) 56 (69.1) 33 (58.9) 23 (41.1) RSVA 13 (8.8) 6 (46.2) 7 (53.8) 6 (7.4) 3 (50.0) 3 (50) RSVBc 19 (12.9) 3 (15.8) 16 (84.2) 2 (2.5) 0 2 (100) HBoV 20 (13.6) 0 20 (100) 4 (4.9) 0 4 (100) FluA 3 (2.0) 0 3 (100) 0 0 0 FluB 1 (0.7) 1 (100) 0 1 (1.2) 0 1 (100) PIV1 1 (0.7) 0 1 (100) 2 (2.5) 2 (100) 0 PIV2 0 0 0 0 0 0 PIV3 12 (8.2) 2 (16.7) 10 (83.3) 4 (4.9) 0 4 (100) PIV4 7 (4.8) 3 (42.9) 4 (57.1) 5 (6.2) 1 (20.0) 4 (80.0) HMPVd 11 (7.5) 3 (27.3) 8 (72.7) 0 0 0 HAdV 23 (15.6) 0 23 (100) 5 (6.2) 2 (40.0) 3 (60.0) NL63 3 (2.0) 0 3 (100) 4 (4.9) 1 (25.0) 3 (75.0) HKU1 1 (0.7) 0 1 (100) 3 (3.7) 1 (33.3) 2 （66.7） OC43 3 (2.0) 1 (33.3) 2 (66.7) 0 0 0 229E 2 (1.4) 0 2 (100) 1 (1.2) 1 (100) 0 Note: a: Single No./Total No.; b: Co-infected No./Total No.; c:χ2 = 5.63466, P < 0.05; d:χ2 = 4.84309, P < 0.05. Table 2. Distribution of viral pathogens in the patient groups determined using the RVP FAST assay
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Groups No. tested No. positive (%) HRV-Ab HRV-Bc HRV-Cd Totala Asthma 147 29 (19.7) 1 (0.7) 47 (32.0) 77 (52.4) Control 81 15 (18.5) 4 (3.7) 10 (12.3) 29 (35.8) Note: a:χ2 = 5.12263, 0.01 <P < 0.05; b:χ2 = 0.19119, P > 0.05; c:χ2 = 2.65242, P > 0.05; d:χ2 = 9.70824, P < 0.05. Table 3. HRV species determined using RVP FAST combined with PCR and sequencing in all patients
Figure 0 个
Table 3 个