Figure 4个  Table 4个
    • Year Samples Influenza (%) Influenza A (%) Influenza B (%)
      2010 9368 1695 (18.09) 1203 (12.84) 492 (5.25)
      2011 6997 1608 (22.98) 1489 (21.28) 119 (1.70)
      2012 13,054 3674 (28.14) 2209 (16.92) 1465(11.22)
      2013 6543 1178 (18.00) 1096 (16.75) 82 (1.25)
      2014 8833 2504 (28.35) 2037 (23.06) 467 (5.29)
      2015 11,427 2826 (24.73) 2124 (18.59) 702 (6.14)
      2016 12,563 2880 (22.92) 1740 (13.85) 1140(9.07)
      2017 15,828 4122 (26.04) 3693 (23.33) 429 (2.71)
      2018 20,261 4760 (23.49) 2382 (11.76) 2378(11.74)
      Total 104,874 25,247 (24.07) 17,973 (17.14) 7274(6.94)

      Table 1.  Annual distribution of influenza cases at Kiang Wu Hospital in Macau, 2010–2018.

    • Variable Samples Influenza A Influenza B
      Number (%) Chi-square Number (%) Chi-square
      Age
      0–4 23,710 3039 (12.82) χ2 = 949.75 658(2.78) χ2 = 1110.6
      5–10 7492 1288 (17.19) P < 2× 10-16 894(11.93) P < 2× 10-16
      11–17 2696 660 (24.48) 236(8.75)
      18–39 11,798 2824 (23.94) 741(6.28)
      40–64 6036 1354 (22.43) 381(6.31)
      > 64 3999 524 (13.10) 92 (2.30)
      Gender
      Female 28,590 5029 (17.59) χ2 = 1.68 1559 (5.45) χ2 = 0.48
      Male 27,141 4660 (17.17) P = 0.1943 1443 (5.32) P = 0.488
      Area
      Local 52,439 8968 (17.10) χ2 = 49.35 2797 (5.33) χ2 = 4.68
      Tourist 3292 721 (21.90) P < 2× 10-12 205(6.23) P = 0.0306
      Season
      Spring 18,288 2357 (12.89) χ2 = 653.94 1901 (10.39) χ2 = 1406.5
      Summer 10,468 2059 (19.67) P < 2× 10-16 341(3.26) P < 2× 10-16
      Autumn 10,568 1566 (14.82) 153(1.45)
      Winter 16,407 3707 (22.59) 607(3.70)

      Table 2.  Chi-square test results of influenza A and B by age, gender, area, and season in normal years.

    • Variables Influenza A in 2017 Influenza A in normal P value
      Samples N (%) P value Samples N (%)
      Age
      0–4 1335 519 (38.9) χ2 = 80.43 1109 83(7.5) < 2× 10-16
      5–10 419 188 (44.9) P =7910-16 269 28(10.4) < 2× 10-16
      11–17 116 68 (58.6) 116 14(12.1) 3× 10-13
      18–39 789 449 (56.9) 549 99(18.0) < 2× 10-16
      40–64 478 253 (52.9) 288 45(15.6) < 2× 10-16
      > 64 324 157 (48.5) 246 30(12.2) < 2× 10-16
      Gender
      Male 1679 784 (46.7) χ2 = 0.31 1289 152 (11.8) < 2× 10-16
      Female 1782 850 (47.7) P = 0.5771 1288 147 (11.4) < 2× 10-16
      Area
      Local 3042 1401 (46.1) χ2 = 13.11 2414 273 (11.3) < 2× 10-16
      Tourist 419 233 (55.6) P < 0.0003 163 26(15.9) < 2× 10-16
      Total 3461 1634 (47.2) 2577 299 (11.6) < 2× 10-16

      Table 3.  Distribution and comparison of influenza A in July 2017.

    • Variables Influenza B in 2012 and 2018 Influenza B in normal Chi-Squre
      Samples N (%) P value Samples N (%)
      Age
      0–4 4369 675 (15.4) χ2 = 566.35 5338 125 (2.3) < 2× 10-16
      5–10 2362 926 (39.2) P < 2× 10-16 1561 129 (8.3) < 2× 10-16
      11–17 647 260 (40.2) 667 32 (4.8) < 2× 10-16
      18–39 2435 714 (29.3) 3302 138 (4.2) < 2× 10-16
      40–64 1275 349 (27.4) 1494 79 (5.3) < 2× 10-16
      > 64 589 110 (18.7) 824 15 (1.8) < 2× 10-16
      Gender
      Male 5498 1384 (25.2) χ2 = 3.11 6321 235 (3.7) < 2× 10-16
      Female 6188 1650 (26.7) P = 0.0779 6885 283 (4.1) < 2× 10-16
      Area
      Local 10,486 2681 (25.6) χ2 = 9.01 12,284 464 (3.8) < 2× 10-16
      Tourist 1191 353 (29.6) P = 0.0027 922 54 (5.9) < 2× 10-16
      Total 11,677 3034 (25.9) 13,206 518 (3.9) < 2× 10-16

      Table 4.  Distribution and comparison of influenza B in January–February 2012 and January–February 2018.