• Alenquer, M., Amorim, M.J., 2015. Exosome biogenesis, regulation, and function in viral infection. Viruses 7, 5066–5083.

  • Bai, J.H.K., Payne, L.N., Skinner, M.A., 1998. Sequence of host-range determinants in the env gene of a full-length, infectious proviral clone of exogenous avian leukosis virus HPRS-103 confirms that it represents a new subgroup (designated J). Avian Dis. 27, S92–S93.

  • Bukong, T.N., Momen-Heravi, F., Kodys, K., Bala, S., Szabo, G., 2014. Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90. PLoS Pathog. 10, e1004424.

  • Chahar, H.S., Bao, X., Casola, A., 2015. Exosomes and their role in the life cycle and pathogenesis of RNA viruses. Viruses 7, 3204–3225.

  • Colombo, M., Raposo, G., Thery, C., 2014. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu. Rev. Cell Dev. Biol. 30, 255–289.

  • Crenshaw, B.J., Gu, L., Sims, B., Matthews, Q.L., 2018. Exosome biogenesis and biological function in response to viral infections. Open Virol. J. 12, 134–148.

  • Dhama, K., Singh, R., Karthik, K., Chakraborty, S., Tiwari, R., Wani, M.Y., Mohan, J., 2014. Artificial insemination in poultry and possible transmission of infectious pathogens: a review. Asian J. Anim. Vet. Adv. 9, 211–228.

  • Fadly, A.M., Smith, E.J., 1999. Isolation and some characteristics of a subgroup J-like avian leukosis virus associated with myeloid leukosis in meat-type chickens in the United States. Avian Dis. 43, 391–400.

  • Federspiel, M.J., Hughes, S.H., 1997. Retroviral gene delivery. Methods Cell Biol. 52, 179–214.

  • Gurunathan, S., Kang, M.H., Jeyaraj, M., Qasim, M., Kim, J.H., 2019. Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes. Cells 8.

  • Johnstone, R.M., Adam, M., Hammond, J.R., Orr, L., Turbide, C., 1987. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J. Biol. Chem. 262, 9412–9420.

  • Kalluri, R., LeBleu, V.S., 2020. The biology, function, and biomedical applications of exosomes. Science 367.

  • Kechin, A., Boyarskikh, U., Kel, A., Filipenko, M., 2017. cutPrimers: a new tool for accurate cutting of primers from reads of targeted next generation sequencing. J. Comput. Biol. 24, 1138–1143.

  • Kumar, A., Kodidela, S., Tadrous, E., Cory, T.J., Walker, C.M., Smith, A.M., Mukherjee, A., Kumar, S., 2020. Extracellular vesicles in viral replication and pathogenesis and their potential role in therapeutic intervention. Viruses 12.

  • Landman, W.J., Post, J., Boonstra-Blom, A.G., Buyse, J., Elbers, A.R., Koch, G., 2002. Effect of an in ovo infection with a Dutch avian leukosis virus subgroup J isolate on the growth and immunological performance of SPF broiler chickens. Avian Pathol. 31, 59–72.

  • Langmead, B., Salzberg, S.L., 2012. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357–359.

  • Li, T., Yao, X., Li, C., Zhang, J., Xie, Q., Wang, W., Lu, H., Fu, H., Li, L., Xie, J., Shao, H., Gao, W., Qin, A., Ye, J., 2020. Gp37 regulates the pathogenesis of avian leukosis virus subgroup J via its C terminus. J. Virol. 94.

  • Lin, Y., Xia, J., Zhao, Y., Wang, F.Y., Yu, S.C., Zou, N.L., Wen, X.T., Cao, S.J., Huang, Y., 2013. Reproduction of hemangioma by infection with subgroup J avian leukosis virus:the vertical transmission is more hazardous than the horizontal way. Virol. J. 10.

  • Longatti, A., 2015. The dual role of exosomes in hepatitis A and C virus transmission and viral immune activation. Viruses 7, 6707–6715.

  • Madison, M.N., Jones, P.H., Okeoma, C.M., 2015. Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex. Virology 482, 189–201.

  • Madison, M.N., Roller, R.J., Okeoma, C.M., 2014. Human semen contains exosomes with potent anti-HIV-1 activity. Retrovirology 11, 102.

  • Malhotra, S., Justice, J., Lee, N., Li, Y., Zavala, G., Ruano, M., Morgan, R., Beemon, K., 2015. Complete genome sequence of an American avian leukosis virus subgroup J isolate that causes hemangiomas and myeloid leukosis. Genome Announc. 3, e01586-01514.

  • Meng, F., Li, Q., Zhang, Y., Cui, Z., Chang, S., Zhao, P., 2018a. Isolation and characterization of subgroup J Avian Leukosis virus associated with hemangioma in commercial Hy-Line chickens. Poultry Sci. 97, 2667–2674.

  • Meng, F., Li, Q., Zhang, Y., Zhang, Z., Tian, S., Cui, Z., Chang, S., Zhao, P., 2018b. Characterization of subgroup J avian Leukosis virus isolated from Chinese indigenous chickens. Virol. J. 15, 33.

  • Muller, L., 2020. Exosomes: nanodust? HNO 68, 56–59.

  • Neoplastic Diseases. Diseases of Poultry. https://doi.org/10.1002/9781119421481.ch1 52013, 513-673.

  • Payne, L.N., Brown, S.R., Bumstead, N., Howes, K., Frazier, J.A., Thouless, M.E., 1991. A novel subgroup of exogenous avian leukosis virus in chickens. J. Gen. Virol. 72 (Pt 4), 801–807.

  • Payne, L.N., Gillespie, A.M., Howes, K., 1993. Unsuitability of chicken sera for detection of exogenous ALV by the group-specific antigen ELISA. Vet. Rec. 132, 555–557.

  • Payne, L.N., Nair, V., 2012. The long view: 40 years of avian leukosis research. Avian Pathol. 41, 11–19.

  • Rubin, H., Fanshier, L., Cornelius, A., Hughes, W.F., 1962. Tolerance and immunity in chickens after congenital and contact infection with an avian leukosis virus. Virology 17, 143–156.

  • Sadri, N.J., Bokharaei-Salim, F., Karimzadeh, M., Moghoofei, M., Karampoor, S., Mirzaei, H.R., Tabibzadeh, A., Jafari, A., Ghaderi, A., Asemi, Z., Mirzaei, H., Hamblin, M.R., 2019. MicroRNAs and Exosomes: Key Players in HIV Pathogenesis. HIV Med.

  • Shen, Y., Cai, L., Wang, Y., Wei, R., He, M., Wang, S., Wang, G., Cheng, Z., 2014. Genetic mutations of avian leukosis virus subgroup J strains extended their host range. J. Gen. Virol. 95, 691–699.

  • Slonchak, A., Clarke, B., Mackenzie, J., Amarilla, A.A., Setoh, Y.X., Khromykh, A.A., 2019. West Nile virus infection and interferon alpha treatment alter the spectrum and the levels of coding and noncoding host RNAs secreted in extracellular vesicles. BMC Genom. 20, 474.

  • Smith, E.J., Fadly, A.M., 1994. Male-mediated venereal transmission of endogenous avian leukosis virus. Poultry Sci. 73, 488–494.

  • Thery, C., Zitvogel, L., Amigorena, S., 2002. Exosomes: composition, biogenesis and function. Nat. Rev. Immunol. 2, 569–579.

  • Urbanelli, L., Buratta, S., Tancini, B., Sagini, K., Delo, F., Porcellati, S., Emiliani, C., 2019. The role of extracellular vesicles in viral infection and transmission. Vaccines (Basel) vol. 7.

  • van Niel, G., D'Angelo, G., Raposo, G., 2018. Shedding light on the cell biology of extracellular vesicles. Nat. Rev. Mol. Cell Biol. 19, 213–228.

  • Venugopal, K., Howes, K., Barron, G.S., Payne, L.N., 1997. Recombinant env-gp85 of HPRS-103 (subgroup J) avian leukosis virus: antigenic characteristics and usefulness as a diagnostic reagent. Avian Dis. 41, 283–288.

  • Vojtech, L., Woo, S., Hughes, S., Levy, C., Ballweber, L., Sauteraud, R.P., Strobl, J., Westerberg, K., Gottardo, R., Tewari, M., Hladik, F., 2014. Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions. Nucleic Acids Res. 42, 7290–7304.

  • Vora, A., Zhou, W., Londono-Renteria, B., Woodson, M., Sherman, M.B., Colpitts, T.M., Neelakanta, G., Sultana, H., 2018. Arthropod EVs mediate dengue virus transmission through interaction with a tetraspanin domain containing glycoprotein Tsp29Fb.Proc. Natl. Acad. Sci. U. S. A. 115, E6604–E6613.

  • Wang, G., Wang, Z., Zhuang, P., Zhao, X., Cheng, Z., 2017. Exosomes carring gag/env of ALV-J possess negative effect on immunocytes. Microb. Pathog. 112, 142–147.

  • Wang, P., Li, M., Li, H., Lin, L., Shi, M., Gu, Z., Gao, Y., Huang, T., Mo, M., Wei, T., Wei, P., 2020. Full-length cDNA sequence analysis of 85 avian leukosis virus subgroup J strains isolated from chickens in China during the years 1988-2018:coexistence of 2 extremely different clusters that are highly dependent upon either the host genetic background or the geographic location. Poultry Sci. 99, 3469–3480.

  • Wang, P., Lin, L., Li, H., Yang, Y., Huang, T., Wei, P., 2018. Diversity and evolution analysis of glycoprotein GP85 from avian leukosis virus subgroup J isolates from chickens of different genetic backgrounds during 1989-2016: coexistence of five extremely different clusters. Arch. Virol. 163, 377–389.

  • Wang, Q., Gao, Y., Wang, Y., Qin, L., Qi, X., Qu, Y., Gao, H., Wang, X., 2012. A 205-nucleotide deletion in the 30 untranslated region of avian leukosis virus subgroup J, currently emergent in China, contributes to its pathogenicity. J. Virol. 86, 12849.

  • Wang, T., Fang, L., Zhao, F., Wang, D., Xiao, S., 2018. Exosomes mediate intercellular transmission of porcine reproductive and respiratory syndrome virus. J. Virol. 92.

  • Welch, J.L., Kaddour, H., Schlievert, P.M., Stapleton, J.T., Okeoma, C.M., 2018. Semen exosomes promote transcriptional silencing of HIV-1 by disrupting NF-kappaB/Sp1/Tat circuitry. J. Virol. 92.

  • Welch, J.L., Madison, M.N., Margolick, J.B., Galvin, S., Gupta, P., Martinez-Maza, O., Dash, C., Okeoma, C.M., 2017. Effect of prolonged freezing of semen on exosome recovery and biologic activity. Sci. Rep. 7, 45034.

  • Zhang, X., Yan, Z., Li, X., Lin, W., Dai, Z., Yan, Y., Lu, P., Chen, W., Zhang, H., Chen, F., Ma, J., Xie, Q., 2016. GADD45beta, an anti-tumor gene, inhibits avian leukosis virus subgroup J replication in chickens. Oncotarget 7, 68883–68893.

  • Zhou, D., Xue, J., Zhang, Y., Wang, G., Feng, Y., Hu, L., Shang, Y., Cheng, Z., 2019. Outbreak of myelocytomatosis caused by mutational avian leukosis virus subgroup J in China, 2018. Transboundary Emerg. Dis. 66, 622–626.

  • Zhou, W., Woodson, M., Neupane, B., Bai, F., Sherman, M.B., Choi, K.H., Neelakanta, G., Sultana, H., 2018. Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells. PLoS Pathog. 14, e1006764.

  • Zhou, Y., McNamara, R.P., Dittmer, D.P., 2020. Purification methods and the presence of RNA in virus particles and extracellular vesicles. Viruses 12.