Figure 8个  Table 2个
    • ORFs Encoded proteins F20 F50 F100 F150 F200
      ORF1a Nsp2 0 (0)* 0 (0) 1 (0.13) 1 (0.13) 1 (0.13)
      Nsp3 0 (0) 1 (0.06) 1 (0.06) 1 (0.06) 1 (0.06)
      ORF1b Nsp13 0 (0) 0 (0) 0 (0) 1 (0.17) 1 (0.17)
      S (1386) S 0 (0) 6 (0.43) 12 (0.87) 13 (0.94) 14 (1.01)
      ORF3 (225) ORF3 0 (0) 0 (0) 1 (0.44) 1 (0.44) 1 (0.44)
      M (227) M 0 (0) 0 (0) 1 (0.44) 1 (0.44) 1 (0.44)
      Total number 0 7 14 18 19
      *Number of aa changes and change rates of the corresponding proteins (%) are indicated in parentheses.

      Table 1.  Statistics of aa change numbers and change rates in the corresponding proteins at different passages.

    • ORFs Amino acid position F20 F50 F100 F150 F200
      ORF1a
        Nsp2 (750) 699 M M L L L
        Nsp3 (1656) 1562 M I I I I
      ORF1b
        Nsp13 (597) 968 A A A T T
      S (1386) 42 Q Q H Q Q
      55–57 IGE K– K– K– K–
      128 F F Y Y Y
      265 D D D A A
      378 D D N N N
      490 T T R R R
      773 K K K K N
      877–878 SG RR RR RR RR
      900 L L L L V
      1009 N N D D D
      1338 I I T T T
      1353 C F F F F
      ORF3 (225) 170 Y Y H H H
      M (227) 159 G G D D D

      Table 2.  Amino acid changes that occurred at different passages.