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H3 numbering HA1 HA2 HI Epitope Sb region 186 188 190 192 120 129 260 154 A/California/4/2009* > 20,480 GLW/18 S T D Q A N N R 2560 LCF/19 P I A E T D D G 320 GLW/18-LCF-HA P I A E T D D G 160 GLW/18-LCF-HA-chimera P I A E A N N R 320 LCF/19-GLW-HA S T D Q A N N R 2560 LCF/19-GLW-HA-chimera S T D Q T D D G 2560 GLW/18-HA-S186P P T D Q A N N R 640 GLW/18-HA-S186P-T188I P I D Q A N N R 160 *A/California/4/2009 RG version is used as a standard strain. Table 1. Genotypes and HI titers of the GLW/18, LCF/19 recombinant viruses and reassorted mutants.
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Year Vaccine type Strain name HA Epitope Sb region 186 188 190 192 Northern hemisphere 2020–2021 Egg-, cell- or recombinant-based A/Guangdong-Maonan/SWL1536/2019 P I A E A/Hawaii/70/2019 P I A E Southern hemisphere 2021 Cell- or recombinant- based A/Wisconsin/588/2019 P I D Q 2021 Egg-based A/Victoria/2570/2019 P I D Q 2020 A/Brisbane/02/2018 P T D Q Table 2. Genotypes of vaccine strains recommended by WHO in the southern and northern hemispheres in 2020–2021.
Figure 4 个
Table 2 个