Figure 6个  Table 1
    • Compound Name PEDV FIPV
      IC50a (µmol/L) CC50b (µmol/L) EC50c (µmol/L) SId values CC50 (µmol/L) EC50 (µmol/L) SI values
      1 3-(aminocarbonyl)-1-phenylpyridinium 0.1877 73.8 28.63 2.58 60.48 59.66 1.01
      2 2, 3-dichloronaphthoquinone 6.765 21.79 38.45 0.56 36.7 46.03 0.80
      a50% inhibitory concentration against PEDV 3CLpro;
      b50% cytotoxic concentration in subcultured cells;
      c50% effective concentration of test compound in inhibiting viral replication;
      dselectivity index (SI = CC50/EC50). The IC50, CC50 and EC50 values were determined using GraphPad Prism 7

      Table 1.  Antiviral activities of compounds 1 and 2 against PEDV and FIPV.