Severe acute hepatitis in children with unknown aetiology, etiology analysis and the next action

Yuan Gao; Leijie Wang; Lin Wang; Fengmin Lu

doi:10.1016/j.virs.2022.07.004

October 2022

Citation: Yuan Gao, Leijie Wang, Lin Wang, Fengmin Lu. Severe acute hepatitis in children with unknown aetiology, etiology analysis and the next action .VIROLOGICA SINICA, 2022, 37(5) : 778-782. http://dx.doi.org/10.1016/j.virs.2022.07.004

Severe acute hepatitis in children with unknown aetiology, etiology analysis and the next action

Yuan Gao ^a ,
Leijie Wang ^b ,
Lin Wang ^b ,
Fengmin Lu ^{b,c
,,}

a The Fourth Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China;
b Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China;
c Hepatology Institute, Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Disease, Peking University People's Hospital, Beijing, 100044, China

Corresponding author: Fengmin Lu, lu.fengmin@hsc.pku.edu.cn,lu.fengmin@bjmu.edu.cn
Received Date: 27 May 2022
Accepted Date: 04 July 2022
Available online: 09 July 2022

Abstract

Highlights
1. MIS-C and severe acute hepatitis might share the common pathogenic mechanism;
2. SARS-CoV-2 persistence throughout multiorgan and tissues;
3. Relationship between COVID-19 vaccines and severe acute hepatitis worth investigating.

Electronic Supplementary Material

10.1016j.virs.2022.07.004-ESM.docx
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