RESEARCHES ON THE HEMAGGLUTININ(HAN) OF HEMORRHAGIC FEVER WITH RENAL SYNDROME VIRUSES (HFRSV) Ⅰ. A PRELIMINARY STUDY ON THE HEMAGGLUTING ACTIVITY OF HFRSV
Abstract: 2-1 day old suckling mice were inoculated ic with 8 HFRSV strains (Chen, A_(216), A_9, H_(8205), C_4, R_(22), 76/118) respectively. The brain tissue of the mice was harvested immediately before death and prepared into HAN by sucrose-acetone method. The HA activity and HI reactivity were tested. It was demonstrated that the HA activity varied with HFRSV strains and was associated with their virulence (LD_(50)) to the suckling mice. There was no cross reaction between HFRSVHAN and other viral immune sera. The...