EFFECT OF CYTOMEGALOVIRUS INFECTION ON THE THYMUS OF NEONATAL GUINEA PIGS

Sc. inoculation of neonatal guinea pigs with guinea pig cytomegalovirus (GPCMV)resulted in acute infection of thymus. Infectious virus could be recovered from the thymus of infected animals at 5 days postinfection and the highest titers ef infections virus appeared at 10 days postinfection. The weights, total numbers of cells and T-rosette ferming cells were significantly lower in the thymus of GPCMV-infected animals tested on days 7 to 16, specially on day 10 postinfection as compared to control animals Al...