Citation: ZENG Fan-Ji. HUMAN CYTOMECALOVIRUS LATENCY IN HUMAN EMBRYONIC FORESKIN CELLS IN VITRO .VIROLOGICA SINICA, 1987, 2(3) : 34.

HUMAN CYTOMECALOVIRUS LATENCY IN HUMAN EMBRYONIC FORESKIN CELLS IN VITRO

  • Available online: 05 September 1987
  • Human cytomegalovirus(HCMV)latency model in human embryonic foreskin cells(HEF)was established with 500ng/ml of Tunicamycin(TM) which is a glucosamine-containing antibiotic that specifically inhibits glycosylation of proteins. Toxic effects in confluent monolayer cultures occurred when more than 500ng/ml of TM was used. The different concentrations of TM reduced the yield of HCMV to varying degrees, however, HCMV was not totally inhibited. At 5 days postinfection HCMV was not detectable at a TM concentratio...

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    HUMAN CYTOMECALOVIRUS LATENCY IN HUMAN EMBRYONIC FORESKIN CELLS IN VITRO

    • 1. Department of Virology

    Abstract: Human cytomegalovirus(HCMV)latency model in human embryonic foreskin cells(HEF)was established with 500ng/ml of Tunicamycin(TM) which is a glucosamine-containing antibiotic that specifically inhibits glycosylation of proteins. Toxic effects in confluent monolayer cultures occurred when more than 500ng/ml of TM was used. The different concentrations of TM reduced the yield of HCMV to varying degrees, however, HCMV was not totally inhibited. At 5 days postinfection HCMV was not detectable at a TM concentratio...

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