Citation: ZHENG Zhi-Ming, LIN Na, ZHANG Wei-Ying, ZHANG Jiang-Hong, ZHU Wei-Ping, HU Jian-Ming. Pathological Observation of Salivary Gland and Spleen in the Newborn Guinea Pigs with Acute Cytomegalovirus Infection .VIROLOGICA SINICA, 1988, 3(3) : 258.

Pathological Observation of Salivary Gland and Spleen in the Newborn Guinea Pigs with Acute Cytomegalovirus Infection

  • Available online: 05 September 1988
  • Subcutaneous inoculation of guinea pig cytomegalovirus (CMV) into newborn guinea pigs resulted in acute CMV infection of the animals. Guinea pigs Infected had growth retardation, salivary gland swelling, and splenomegaly. Virus could be recovered from salivary gland 5 days after ineeulation and the infectivity titers of CMV reached to a high titer of 3.7 log_(10)TCID_(50)/0.1 ml of 10% salivary gland suspensions 16 days after inoculation, Histopathological examination showed that CMV mainly caused degenerat...

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    Pathological Observation of Salivary Gland and Spleen in the Newborn Guinea Pigs with Acute Cytomegalovirus Infection

    • 1. Virus Research Institute
    • 2. Hubei Medical College
    • 3. Wuhan

    Abstract: Subcutaneous inoculation of guinea pig cytomegalovirus (CMV) into newborn guinea pigs resulted in acute CMV infection of the animals. Guinea pigs Infected had growth retardation, salivary gland swelling, and splenomegaly. Virus could be recovered from salivary gland 5 days after ineeulation and the infectivity titers of CMV reached to a high titer of 3.7 log_(10)TCID_(50)/0.1 ml of 10% salivary gland suspensions 16 days after inoculation, Histopathological examination showed that CMV mainly caused degenerat...

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