Citation: CAO Zong-Li, CHOU Su-Ying, DONG Jie-De, CHEN Chen-Hua, ZENG Li, YU Xiu-Beng, SONG Yuan-Di. Transformation of Human Embryonic Lung Cells by Ultraviolet Irradiation Inactivated Herpes Simplex Virus Type 2 .VIROLOGICA SINICA, 1988, 3(3) : 265.

Transformation of Human Embryonic Lung Cells by Ultraviolet Irradiation Inactivated Herpes Simplex Virus Type 2

  • Available online: 05 September 1988
  • Three transformed human cell lines were obtained after infection of human embryo lung cells with ultraviolet irradiation inactivated HSV-2. The transformed cells appear polygonal resembling epithelial cells. They are morphologically compatible with neoplastic cells, Chromosome examination showed hyperdiploid karyotype. In vitro, afftcr eonfluency of monolayers they continue to grow into pyramidal masses indicating loss of contact inhibition. Indirect immunoenzymatic test revealed the presence of HSV antigen...

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    Transformation of Human Embryonic Lung Cells by Ultraviolet Irradiation Inactivated Herpes Simplex Virus Type 2

    • 1. Department of Microbiology
    • 2. Shandong Medical University

    Abstract: Three transformed human cell lines were obtained after infection of human embryo lung cells with ultraviolet irradiation inactivated HSV-2. The transformed cells appear polygonal resembling epithelial cells. They are morphologically compatible with neoplastic cells, Chromosome examination showed hyperdiploid karyotype. In vitro, afftcr eonfluency of monolayers they continue to grow into pyramidal masses indicating loss of contact inhibition. Indirect immunoenzymatic test revealed the presence of HSV antigen...

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