Study on Vector Homology in Clinical Specimens with Cloned Probes
Abstract: Nucleic acid hybridization techniques using cloned probes (recombinantplasmids composed of viral fragment and bacterial plasmid vector, such as pBR322)are applied in assay of clinical specimen in research and diagnostic laborato-ries. They have simple, quick and sensitive adventages, and help to detectthose virus gene that are difficult or impossible to culture. However, it should be noted that there may be a homology problem between cloued probe and cli-nical specimens. We detected 213 specimens from 173 p...