The Study on Antiviral Effect of Methanol Extract of Rubia cordifolia against Herpes Simplex Virus 2 in vitro

Rubia cordifolia is a traditional Chinese drug. In this paper, it was reported that the methanol extract of this drug showed significant antiviral effect against herpes simplex virus 2 in vitro. In Vero cell line, virus inhibiting index reached 3 log. Virus reproduction inhibiting test showed that the reproduction of infectious virus parlicles was inhibited. By comparing the antiviral effect of this agent in different cell line, it was found that the antiviral effect of this extract was cell line dependent.