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Volume 05 Issue 2
April 1990
    Citation: WANG Hai-Chao, Chen Wan-Rong, JIANG Yu-Tu. The Preparation of Monoclonal Anti-idiotypic Antibodies Against Mouse Monoclonal Anti-HBs and Their Immunogenicity Ⅱ.The Study on Immunogenicity of Ab_2-1 .VIROLOGICA SINICA, 1990, 5(2) : 162.
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    The Preparation of Monoclonal Anti-idiotypic Antibodies Against Mouse Monoclonal Anti-HBs and Their Immunogenicity Ⅱ.The Study on Immunogenicity of Ab_2-1

    • 1.

      Institute of Microbiology and Epidemiology Academy of Military Medical Sciences

    • 2.

      Beijing 100071

    • Available online: 05 June 1990
    • The Ab_2-1 was used to immunize four BALB/c mice and two rabbits. Each mouse recievcd inoculation of 100μg of Ab_2-1 for four times intraperitoneally. Each rabbit was injected with 1 mg of Ab_2-1 for four times subctaneously. All the mice and rabbits immunized with Ab_2-1 produced anti-HBs antibodies, specificity of which also was confirmed by two types of competitive inhibition test(SPRIA). The titers of mouse anti-HBs were from 2~(-6) to 2~(-9) the anti-HBs titers of rabbit sera varied from 2~(-10) to 2~(...
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      The Preparation of Monoclonal Anti-idiotypic Antibodies Against Mouse Monoclonal Anti-HBs and Their Immunogenicity Ⅱ.The Study on Immunogenicity of Ab_2-1

      • 1. Institute of Microbiology and Epidemiology Academy of Military Medical Sciences
      • 2. Beijing 100071

      Abstract: The Ab_2-1 was used to immunize four BALB/c mice and two rabbits. Each mouse recievcd inoculation of 100μg of Ab_2-1 for four times intraperitoneally. Each rabbit was injected with 1 mg of Ab_2-1 for four times subctaneously. All the mice and rabbits immunized with Ab_2-1 produced anti-HBs antibodies, specificity of which also was confirmed by two types of competitive inhibition test(SPRIA). The titers of mouse anti-HBs were from 2~(-6) to 2~(-9) the anti-HBs titers of rabbit sera varied from 2~(-10) to 2~(...

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