Citation: ZHANG Yong-Yuan, YAN Pu, WANG You-Kun, Yu-Zhi-Qun, HAO Lian-Jie. Comparison of Two Pre-s Proteins in Hepatocytes with HBV Replication Status by in situ HBV DNA Hybridization Assay .VIROLOGICA SINICA, 1990, 5(4) : 435.

Comparison of Two Pre-s Proteins in Hepatocytes with HBV Replication Status by in situ HBV DNA Hybridization Assay

  • Available online: 05 December 1990
  • To compare relationship between two pre-s proteins and HBV replication HBV DNA in situ hybridization was applied to a group of patients with chronic hepatitis by bio-probe, in conjunction of detection of intrahepatic HBsAg, HBcAg, pre-s1 and pre-s2 antigens. It was found that the positive rate for pre-s1 was up to 75%(15/20), being significantly higher than that of pre-s2 (35%) in the same group. More importantly the presence of pre..sl, rather than pre-s2, was in parallel with the presence of intrahepatic ...

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    Comparison of Two Pre-s Proteins in Hepatocytes with HBV Replication Status by in situ HBV DNA Hybridization Assay

    • 1. Clinical Immunology Research Unit
    • 2. Tongji Hospital

    Abstract: To compare relationship between two pre-s proteins and HBV replication HBV DNA in situ hybridization was applied to a group of patients with chronic hepatitis by bio-probe, in conjunction of detection of intrahepatic HBsAg, HBcAg, pre-s1 and pre-s2 antigens. It was found that the positive rate for pre-s1 was up to 75%(15/20), being significantly higher than that of pre-s2 (35%) in the same group. More importantly the presence of pre..sl, rather than pre-s2, was in parallel with the presence of intrahepatic ...

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