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Volume 06 Issue 2
April 1991
    Citation: CHEN Zhang-Lin, JIANG Zi-Sheng, DAI Zhi-Fang, YUAN Keng, PENG Min. Purification and Characterization of HFRS Virus Glycoproteins .VIROLOGICA SINICA, 1991, 6(2) : 143.
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    Purification and Characterization of HFRS Virus Glycoproteins

    • 1.

      Jiangxi Institute of Medical Sciences

    • 2.

      Nanchang 330006

    • Available online: 05 June 1991
    • Two HFRS virus glycoproteins with molecular weight of 78K and 57K were purified by immunoaffinity chromatography with preparative SDS-PAGE from virus-infected cells Purified 78K and 57K glycoproteins all showed only one band on SDS-PAGE and have antigenieity and immunogenicity, The results of hemagglutination test indicate that 57K glyeoprotein has hemagglutation activity. Neutralizing test with antisera confirm both 78K and 57K glyeoproteins have neutralizing antigenic determinants. These results suggest t...
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      Purification and Characterization of HFRS Virus Glycoproteins

      • 1. Jiangxi Institute of Medical Sciences
      • 2. Nanchang 330006

      Abstract: Two HFRS virus glycoproteins with molecular weight of 78K and 57K were purified by immunoaffinity chromatography with preparative SDS-PAGE from virus-infected cells Purified 78K and 57K glycoproteins all showed only one band on SDS-PAGE and have antigenieity and immunogenicity, The results of hemagglutination test indicate that 57K glyeoprotein has hemagglutation activity. Neutralizing test with antisera confirm both 78K and 57K glyeoproteins have neutralizing antigenic determinants. These results suggest t...

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