Citation: CAO Zhi-Hui, CHEN Shen-Bao, DING Ru-Ning, ZHOU Yao-Xi. Inhibitory Effect of HSV Infection in Vitro on IgG and Effect of TNF and r-IFN on It .VIROLOGICA SINICA, 1991, 6(3) : 183.

Inhibitory Effect of HSV Infection in Vitro on IgG and Effect of TNF and r-IFN on It

  • Available online: 05 September 1991
  • We successfully established a system in vitro that HSV-Ⅰ infected human tonsillar lymphocytes. Tonsillar lymphocytes prestimulated with PWM(10μg/ml) were infected by living HSV-Ⅰ, so as to their proliferation and IgG synthesis were abated significantly(P<0.005).In the supernatants, the infective titers ofHSV-Ⅰ were about 10~(3?2)—10~(5?7) TCID_(50)/ml,number of viral antigen positive cells about 3%—8%.We found that some lymphokine and monokine can dampen the inhibition of infection of infectious HSV-Ⅰ Th...

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    Inhibitory Effect of HSV Infection in Vitro on IgG and Effect of TNF and r-IFN on It

    • 1. Dept.of Microbiology
    • 2. Nanjing Medical College

    Abstract: We successfully established a system in vitro that HSV-Ⅰ infected human tonsillar lymphocytes. Tonsillar lymphocytes prestimulated with PWM(10μg/ml) were infected by living HSV-Ⅰ, so as to their proliferation and IgG synthesis were abated significantly(P<0.005).In the supernatants, the infective titers ofHSV-Ⅰ were about 10~(3?2)—10~(5?7) TCID_(50)/ml,number of viral antigen positive cells about 3%—8%.We found that some lymphokine and monokine can dampen the inhibition of infection of infectious HSV-Ⅰ Th...

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