Preliminary Studies on Cellular Receptor for Dengue-2 Virus
Abstract: To investigate the role of viral receptor in the initiation of dengue virus infection, viral attachment rates (AR) on Aedes albopictus cell (C6/36), human monocyte-like cell (U937), human T4 (H9),B lymphoblastoid cell(Raji), mouse myeloma cell (SP2/0) and mouse fibroblast cell (L929) were calculated by measuring the residual virus concentration after inoculating a known dose of Den-2 virus upon the above 6 cell lines and then keeping the cells at 4℃ for 15, 30 and 90 mino.The results showed that the ARs of ...