Observation of HFRSV Inclusion Bodies under Ordinary Optical Microscope with APAAP Immunohistochemical Technique in Two HFRSV Sensitive Cell Lines
Abstract: Investigation of the HFRSV inclusion bodies was carried out under ordinary optical microscope with APAAP(alkaline phosphatase anti-alkaline phosphatase)immunohistochemical technique in the Hep-2 and Wish cell lines infected by HFRSV (Hemorrhagic fever with Renal syndrome virus). It was found that there are three types of virus inclusion bodies, central, pheripheral and shedding types. All these findings were verified by electron microscopy, These results have great significance for further understanding the...