Citation: Leonard J Rosenthal, Shang Shi-zhang, Anita Inamdar. Identification of the Morphological Transforming Regions of Human Cytomegalovirus .VIROLOGICA SINICA, 1991, 6(4) : 281.

Identification of the Morphological Transforming Regions of Human Cytomegalovirus

  • Available online: 05 December 1991

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    Identification of the Morphological Transforming Regions of Human Cytomegalovirus

    • 1. Department of Microbiology Georgetown University Medical Center Washington
    • 2. Jinan University Medical College
    • 3. Department of Microbiology Georgetown University Medical Center Washington
    • 4. D.C.20007 USA

    Abstract: DNA of human cytomegalovirus (HCMV) contains three transforming fragments, which have been mapped in the long unique region of the viral genome(see Fig.1). A minimal region of 558 base pairs(bp) (pCM4127) was localized in the XbaI-Hindlll fragment of HCMV strain AD169 (mapunit 0.123—0.140)and designated morphological transforming region Ⅰ (mtrⅠ). MtrⅠwas reported to cause one-step focal transformation of primary Wistar

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