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Volume 07 Issue 2
April 1992
    Citation: YIN Shu-Rong, LIU Yu-Tang, TIAN Xin, BAO Zuo-Yi, JIANG Yu-Tu, ZHANG Xi-Tan. Preliminary Report of Cell Culture of Hepatitis E Virus .VIROLOGICA SINICA, 1992, 7(2) : 134.
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    Preliminary Report of Cell Culture of Hepatitis E Virus

    • 1.

      Institute of Microbiology and Epdemiology

    • 2.

      Academy of Military Medical Sciences

    • Available online: 05 June 1992
    • Hepatitis E virus(HEV) was isolated in human embryomic lung cell inoculated with liver tissue suspension from an HEV-infected rhesus monkey, Slight cytopathic effect(CPE) appeared at the 27th day after 4 blind passages of viruses in cell culturs to at 17th day after 7 passages. Low amounts of 27—34nm virus-like particles(VLPs) in cell cultures were visualized by immunoelectronmicroseopy(IEM). 2 of 3 rhesus monkeys inoculated with 20ml of pool of cell cultures from 4 to 7 passages developed significant eleva...
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      Preliminary Report of Cell Culture of Hepatitis E Virus

      • 1. Institute of Microbiology and Epdemiology
      • 2. Academy of Military Medical Sciences

      Abstract: Hepatitis E virus(HEV) was isolated in human embryomic lung cell inoculated with liver tissue suspension from an HEV-infected rhesus monkey, Slight cytopathic effect(CPE) appeared at the 27th day after 4 blind passages of viruses in cell culturs to at 17th day after 7 passages. Low amounts of 27—34nm virus-like particles(VLPs) in cell cultures were visualized by immunoelectronmicroseopy(IEM). 2 of 3 rhesus monkeys inoculated with 20ml of pool of cell cultures from 4 to 7 passages developed significant eleva...

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