Citation: HE Dai-Fen, WANG Xun-Zhang, XIE Wei-Dong, CHEN Ru, LONG Qi-Xin, DENG Ri-Jiang, BO Zhe-Long, SU De-Meng. Expression of Hepatitis B Virus Surface Antigen Using a Baculovirus Vector with the Polyhedrin Gene .VIROLOGICA SINICA, 1992, 7(4) : 389.

Expression of Hepatitis B Virus Surface Antigen Using a Baculovirus Vector with the Polyhedrin Gene

  • Available online: 05 December 1992
  • Using a polyhedrin-positive transfer plasmid and a nonoccluded (OCC-) parental recombinant, an occluded (OCC~+)recombinant baculovirusdesignated TnNPV-HBs85-OCC~+ was successfully constructed which contained the gene coding for the hepatitis B virus surface antigen under the dual control of the synthetic and XIV promoters, Infection of Tvichoplusia ni larvae with TnNPVHBs85-OCC~+ can be introduced as a contaminant of the diet rather than the conventional baculovirus OCC~- expression vector in which the reco...

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    Expression of Hepatitis B Virus Surface Antigen Using a Baculovirus Vector with the Polyhedrin Gene

    • 1. Institute of Entomology
    • 2. Zhongshan University and National Laboratory of Biological Control

    Abstract: Using a polyhedrin-positive transfer plasmid and a nonoccluded (OCC-) parental recombinant, an occluded (OCC~+)recombinant baculovirusdesignated TnNPV-HBs85-OCC~+ was successfully constructed which contained the gene coding for the hepatitis B virus surface antigen under the dual control of the synthetic and XIV promoters, Infection of Tvichoplusia ni larvae with TnNPVHBs85-OCC~+ can be introduced as a contaminant of the diet rather than the conventional baculovirus OCC~- expression vector in which the reco...

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