Cleavage of the Spike Protein and Cytopathogenesis of Avian Infectious Bronchitis Virus

Studies on paramyxoviruses and myxoviruses have shown that the viral pathogenesis is related to the cleavibility of the viral spike protein, in turn, cleavibility of the spike protein is determined by the amino acid sequence of the connecting peptide of the spike protein This paper intended to investigate the pathogenesis of avian coronavirus, infectious bronchitis virus(IBV) by looking into three aspects, i. e. cytopathogenesis of the virus, cleavage status of the viral spike protein and amino acid sequenc...