Establishment of a Sensitive ELISA for Detecting Antibodies against hepatitis E Virus Based on Synthetic Peptides
Abstract: sensitive ELISA for detection of antibodies against hepatitis E virus(anti-HEV)was established,based on three synthetic peptides from open readin franmes ORF1,ORF2 and ORF3 of the HEVgenome.sera were tested for anti-HEV with our ELISA,One hundred and tWo(97.1%)out of 105sera from patients with enterically transmitted non-A non-B hepatitis E in Chil1a,Burma,India and former USSR were tested positive.A total of 99 sera from normal individuals in Beijing were tested negative.sera from experimentally infected c...