Citation: HUANG Sheng-Hai, SHI Bai-Fen, WANG Meng-Li, ZHANG Yong-Na, HU Yong, BI Ke-Ju. Identification and primary application of fusion-inhibiting active monoclonal antibody of respira- tory syncytial virus .VIROLOGICA SINICA, 2000, 15(1) : 34.

Identification and primary application of fusion-inhibiting active monoclonal antibody of respira- tory syncytial virus

  • Available online: 05 March 2000
  • Monoclonal antibody of F 3 hybridoma cell strain against RSV specific antigen was prepared by hybridoma and tested by indirect immunofluorescence and ELISA. It has neutralizing and fusion inhibiting activity. The neutralizing titres and fusion inhibiting titres of ascites of mice are 1∶128 and 1∶64 respectively. Clinical diagnosis by comparing McAb of F 3 strain with fixed McAb of commerical kit show that the positive according rate are 96.9% and negative according rate are 100%. F 3 hybridoma cell strain probably produces a monoclonal antibody against fusion protein of RSV.

  • 加载中
  • 加载中

Article Metrics

Article views(4183) PDF downloads(947) Cited by()

Related
Proportional views

    Identification and primary application of fusion-inhibiting active monoclonal antibody of respira- tory syncytial virus

    • 1. Anhui Medical University

    Abstract: Monoclonal antibody of F 3 hybridoma cell strain against RSV specific antigen was prepared by hybridoma and tested by indirect immunofluorescence and ELISA. It has neutralizing and fusion inhibiting activity. The neutralizing titres and fusion inhibiting titres of ascites of mice are 1∶128 and 1∶64 respectively. Clinical diagnosis by comparing McAb of F 3 strain with fixed McAb of commerical kit show that the positive according rate are 96.9% and negative according rate are 100%. F 3 hybridoma cell strain probably produces a monoclonal antibody against fusion protein of RSV.

    Relative (20)

    目录

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return