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Volume 15 Issue 3
June 2000
    Citation: YANG Jun, ZHANG Hua-Yuan, WANG You-Chun, MAO Qun-Ying, LI He-Min. Partial sequence com parison of three sporadic hepatitis E variants .VIROLOGICA SINICA, 2000, 15(3) : 232-236.
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    Partial sequence com parison of three sporadic hepatitis E variants

    • 1.

      National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050，China

    • Available online: 05 September 2000
    • Partial genomes of three strains of sporadic hepatitis E virus (Ch T11,Ch T21,Ch T40) were cloned and sequenced. The nucleotide and putative amino acid homology of Ch T11,Ch T21,Ch T40 and other HEV strains were 78.3 81.3% and 95.8 97.9%, respectively. The nucleotide homology between Ch T21 and Ch T40 was 98.8%, while the nucleotide homology of Ch T11 and Ch T21,Ch T40 was 89.8% and 90.2%, respectively. The amino acid homology among Ch T11,Ch T21 and Ch T40 was 100%. Phylogenetic analysis suggested that Ch T11, Ch T21 and Ch T40 may represent a new genotype of HEV.
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      Partial sequence com parison of three sporadic hepatitis E variants

      • 1. National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050，China

      Abstract: Partial genomes of three strains of sporadic hepatitis E virus (Ch T11,Ch T21,Ch T40) were cloned and sequenced. The nucleotide and putative amino acid homology of Ch T11,Ch T21,Ch T40 and other HEV strains were 78.3 81.3% and 95.8 97.9%, respectively. The nucleotide homology between Ch T21 and Ch T40 was 98.8%, while the nucleotide homology of Ch T11 and Ch T21,Ch T40 was 89.8% and 90.2%, respectively. The amino acid homology among Ch T11,Ch T21 and Ch T40 was 100%. Phylogenetic analysis suggested that Ch T11, Ch T21 and Ch T40 may represent a new genotype of HEV.

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