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Volume 17 Issue 4
August 2002
    Citation: TANG Xing—san, DONG Chang—yuan’’, GUO Shu—fang, CHEN Xiao, CHEN Dong—e, GUI Yi—rui, LU Li—li, LUO Xiang. Effect of Interaction Between BTV-Hbc and Different Species Cell and Charateristics of Group Specific Antigen .VIROLOGICA SINICA, 2002, 17(4) : 362-366.
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    Effect of Interaction Between BTV-Hbc and Different Species Cell and Charateristics of Group Specific Antigen

    • 1.

      Institute of Virology，Medical College，Wuhan University，Wuhan 430071，China

    • Available online: 05 November 2002
    • Bluetongue virus(BTV)HbC strain and BTV 10(the international standard strain)were respectively inoculated onto the different species monolayer cells such as Vero cell(monkey renal cel1)， C6 cell(mouse neuroglioma cel1)and Hela cell(human cervical cancer cel1)．We studied comparatively the replicated characteristics of BTV—HbC in different species cells，with BTV 10 in the same cells， morphologic characteristics under microscopy and electron microscopy after interaction between BTV— HbC and different cells．the serologic relation between BTV—HbC and BTV一10．It is further proved that the BTV—HbC strain is probably a new type of Bluetongue virus when connecting our previous re— search about BTV—HbC genome map and RT—PCR analyses of BTV—HbC gene coding group speci fic antigen．
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      Effect of Interaction Between BTV-Hbc and Different Species Cell and Charateristics of Group Specific Antigen

      • 1. Institute of Virology，Medical College，Wuhan University，Wuhan 430071，China

      Abstract: Bluetongue virus(BTV)HbC strain and BTV 10(the international standard strain)were respectively inoculated onto the different species monolayer cells such as Vero cell(monkey renal cel1)， C6 cell(mouse neuroglioma cel1)and Hela cell(human cervical cancer cel1)．We studied comparatively the replicated characteristics of BTV—HbC in different species cells，with BTV 10 in the same cells， morphologic characteristics under microscopy and electron microscopy after interaction between BTV— HbC and different cells．the serologic relation between BTV—HbC and BTV一10．It is further proved that the BTV—HbC strain is probably a new type of Bluetongue virus when connecting our previous re— search about BTV—HbC genome map and RT—PCR analyses of BTV—HbC gene coding group speci fic antigen．

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