The Study on the Infection of Rabbits with Bovine Foamy Virus 3026’
Abstract: Abstract:Rabbits were injected with a single intravenation of Bovine foamy virus 3026(BFV3026)· infected cells in the ear and monitored for sera-conversion serologically up t0 l year.Results of the serological an d virus-rescue assays indicated that all animals were persistently infected with BFV3026 an d showed sustained BFV3O26.spec ific humoral immune response.BFv3026 Was rescued by co-cultivation with fetal bovine lung(FBL)cells from the spleen,kidney,lung,liver and peripheral blood leukocytes of the infected an imals.Virus sequence in poZ was、recovered an d amplified from the tissues where the virus Was rescued from,such as from the heart,brain,bone marrow,mesentery an d the pan creas.In addition.BFv transcripts could be detected in PBL by RT.PCR. S animal model might be usefulfor studyingtheinteractionbe tweenBFv an dBIV