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Volume 19 Issue 3
June 2004
    Citation: MA Xun, LU Cheng-ping, MENG Ji-hong. Epidemic Investigation of Swine Hepatitis E Virus Infection in Xinjiang Region .VIROLOGICA SINICA, 2004, 19(3) : 285-287.
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    Epidemic Investigation of Swine Hepatitis E Virus Infection in Xinjiang Region

    • 1.

      1.Key Laboratory of Animal Disease Diagnostic ＆ Immunology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, China

    • 2.

      Department of Microbiology and Immunology , Southeast University School of Medicine , Nanjing 210009 , China

    • Corresponding author: LU Cheng-ping, 
    • Available online: 20 June 2004
    • The purpose of the present study was to determine the prevalence of swine Hepatitis E virus (HEV) infection in Xinjiang. 813 swine serum samples collected from 1 to 12 months of age at 9 swine farms in Xinjiang region were tested by ELISA for the presence of IgG antibodies against HEV. The recombinant protein pUS166 containing region 452-617aa of the ORF2 of HEV US strain was used as coating antigen. The result showed that anti –HEV IgG were detected in 265 of 405 pigs (65.43%) in one group and 238 of 408 pigs (58.33%) in another group , and that the seropositivity rate was not related to geographic district and breeds, but differed remarkably by age, being 40% among the 1- to 3-month-old piglets, but 77.33% among ones over 3-month-old. It suggested that swine HEV was widespread in different geographic regions of XinJiang.
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      Epidemic Investigation of Swine Hepatitis E Virus Infection in Xinjiang Region

        Corresponding author: LU Cheng-ping,
      • 1. 1.Key Laboratory of Animal Disease Diagnostic ＆ Immunology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, China
      • 2. Department of Microbiology and Immunology , Southeast University School of Medicine , Nanjing 210009 , China

      Abstract: The purpose of the present study was to determine the prevalence of swine Hepatitis E virus (HEV) infection in Xinjiang. 813 swine serum samples collected from 1 to 12 months of age at 9 swine farms in Xinjiang region were tested by ELISA for the presence of IgG antibodies against HEV. The recombinant protein pUS166 containing region 452-617aa of the ORF2 of HEV US strain was used as coating antigen. The result showed that anti –HEV IgG were detected in 265 of 405 pigs (65.43%) in one group and 238 of 408 pigs (58.33%) in another group , and that the seropositivity rate was not related to geographic district and breeds, but differed remarkably by age, being 40% among the 1- to 3-month-old piglets, but 77.33% among ones over 3-month-old. It suggested that swine HEV was widespread in different geographic regions of XinJiang.

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