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Volume 19 Issue 6
December 2004
    Citation: LI Bao-quan, PENG Jun, NIU Zhong-xiang*, JIANG Shi-jin. An Anti-species-sharing-idiotypic Antibody to AIV Bearing the Internal Image of Hemagglutinin on AIV .VIROLOGICA SINICA, 2004, 19(6) : 624-626.
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    An Anti-species-sharing-idiotypic Antibody to AIV Bearing the Internal Image of Hemagglutinin on AIV

    • 1.

      College of Animal Sciences and Technology, Shandong Agricultural University, Taian 271018, China

    • Available online: 20 December 2004
    • One anti-idiotypic monoclonal antibody（a-Id Mab）was raised directed to both rabbit and chicken IgG against Avian influenza virus(AIV). The Mab was able to inhibit the binding of AIV to anti-AIV IgG and specific in binding anti-H9-subtype-AIV IgG. Another experiment demonstrated that the Mab might induce chicken to generate hemagglutination inhibition antibodies. These results indicated this anti-species-sharing-idiotypic antibody bore the internal image of hemagglutinin on AIV.
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      An Anti-species-sharing-idiotypic Antibody to AIV Bearing the Internal Image of Hemagglutinin on AIV

      • 1. College of Animal Sciences and Technology, Shandong Agricultural University, Taian 271018, China

      Abstract: One anti-idiotypic monoclonal antibody（a-Id Mab）was raised directed to both rabbit and chicken IgG against Avian influenza virus(AIV). The Mab was able to inhibit the binding of AIV to anti-AIV IgG and specific in binding anti-H9-subtype-AIV IgG. Another experiment demonstrated that the Mab might induce chicken to generate hemagglutination inhibition antibodies. These results indicated this anti-species-sharing-idiotypic antibody bore the internal image of hemagglutinin on AIV.

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