Citation: LI Bao-quan, PENG Jun, NIU Zhong-xiang*, JIANG Shi-jin. An Anti-species-sharing-idiotypic Antibody to AIV Bearing the Internal Image of Hemagglutinin on AIV .VIROLOGICA SINICA, 2004, 19(6) : 624-626.

An Anti-species-sharing-idiotypic Antibody to AIV Bearing the Internal Image of Hemagglutinin on AIV

  • Available online: 20 December 2004
  • One anti-idiotypic monoclonal antibody(a-Id Mab)was raised directed to both rabbit and chicken IgG against Avian influenza virus(AIV). The Mab was able to inhibit the binding of AIV to anti-AIV IgG and specific in binding anti-H9-subtype-AIV IgG. Another experiment demonstrated that the Mab might induce chicken to generate hemagglutination inhibition antibodies. These results indicated this anti-species-sharing-idiotypic antibody bore the internal image of hemagglutinin on AIV.

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    An Anti-species-sharing-idiotypic Antibody to AIV Bearing the Internal Image of Hemagglutinin on AIV

    • 1. College of Animal Sciences and Technology, Shandong Agricultural University, Taian 271018, China

    Abstract: One anti-idiotypic monoclonal antibody(a-Id Mab)was raised directed to both rabbit and chicken IgG against Avian influenza virus(AIV). The Mab was able to inhibit the binding of AIV to anti-AIV IgG and specific in binding anti-H9-subtype-AIV IgG. Another experiment demonstrated that the Mab might induce chicken to generate hemagglutination inhibition antibodies. These results indicated this anti-species-sharing-idiotypic antibody bore the internal image of hemagglutinin on AIV.

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