Genetic and Immunogenic Characteristics of Measles Virus Isolated in Zhejiang Province
Abstract: In order to elucidate the relationship between genetic characteristics and measles outbreak,and the influence of antigenic variation on measles vaccine effect,we investigated the genetic characteristics and antigenic variation of measles viruses isolated in Zhejiang province during 1999~ 2003.Rats were immunized with the measles virus isolated from patients and the titers of the antibody were measured by cross neutralization test using the antigen of the isolated measles virus,vaccine strains of Shanghai191...