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Volume 31 Issue 3
June 2016
    Citation: Flavia Adriana Zanetti, Romina Cardona, Carlos Rodolfo Federico, Silvina Chimeno-Zoth, Gabriela Calamante. Recombinant canarypox virus expressing the VP2 protein of infectious bursal disease virus induces protection in vaccinated SPF chickens .VIROLOGICA SINICA, 2016, 31(3) : 266-269.  http://dx.doi.org/10.1007/s12250-015-3680-6
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    Recombinant canarypox virus expressing the VP2 protein of infectious bursal disease virus induces protection in vaccinated SPF chickens

    Protection against IBDV by CN048-VP2 vector

    cstr: 32224.14.s12250-015-3680-6
    • 1.

      Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Rivadavia 1917 (C1033AAJ), Ciudad Autónoma de Buenos Aires, Argentina

    • 2.

      Instituto de Biotecnología, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria (INTA), Buenos Aires, Argentina

    • Corresponding author: Gabriela Calamante, calamante.gabriela@inta.gob.ar, ORCID: 0000-0003-3968-190X
    • * Present address: Instituto de Ciencia y Tecnología, Saladillo 2468, (C1440FFX) Ciudad Autónoma de Buenos Aires, Argentina
    • Published Date: 18 March 2016
      Available online: 01 April 2016
    • Infectious bursal disease virus (IBDV) causes infectious bursal disease, a highly contagious immunosuppressive disease that affects young chickens and causes economic losses in the poultry industry worldwide. IBDV replicates mainly in actively dividing B lymphocytes within the bursa of Fabricius (BF), leading to immunosuppression in affected flocks (Mahgoub et al., 2012). Viral protein 2 (VP2), the only structural component of the IBDV icosahedral capsid, is the major antigen responsible for inducing protective immunity in the host (Mahgoub et al., 2012).
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      Recombinant canarypox virus expressing the VP2 protein of infectious bursal disease virus induces protection in vaccinated SPF chickens

        Corresponding author: Gabriela Calamante, calamante.gabriela@inta.gob.ar
      • 1. Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Rivadavia 1917 (C1033AAJ), Ciudad Autónoma de Buenos Aires, Argentina
      • 2. Instituto de Biotecnología, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria (INTA), Buenos Aires, Argentina
      • Published Date: 18 March 2016

      Abstract: Infectious bursal disease virus (IBDV) causes infectious bursal disease, a highly contagious immunosuppressive disease that affects young chickens and causes economic losses in the poultry industry worldwide. IBDV replicates mainly in actively dividing B lymphocytes within the bursa of Fabricius (BF), leading to immunosuppression in affected flocks (Mahgoub et al., 2012). Viral protein 2 (VP2), the only structural component of the IBDV icosahedral capsid, is the major antigen responsible for inducing protective immunity in the host (Mahgoub et al., 2012).

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