For best viewing of the website please use Mozilla Firefox or Google Chrome.
Citation: Peiqi Yin, Zhi Hong, Leiliang Zhang, Youyang Ke. Retromer localizes to autophagosomes during HCV replication [J].VIROLOGICA SINICA, 2017, 32(3) : 245-248.  http://dx.doi.org/10.1007/s12250-016-3914-2

Retromer localizes to autophagosomes during HCV replication

  • In summary, we propose a model for the role of retromer in HCV replication. Upon HCV infection, retromer may provide double-membrane autophagosomal membranes for HCV replication. Our studies suggested a novel link between retromer and autophagy in HCV replication, which may provide new therapeutic targets for antiviral therapy.

  • 加载中
    1. Burd C, Cullen PJ. 2014. Cold Spring Harb Perspect Biol, 6.

    2. Dengjel J, Hoyer-Hansen M, Nielsen MO, et al. 2012. Mol Cell Proteomics, 11: M111.014035.

    3. Dreux M, Gastaminza P, Wieland SF, et al. 2009. Proc Natl Acad Sci U S A, 106: 14046–14051.
        doi: 10.1073/pnas.0907344106

    4. Estrabaud E, De Muynck S, Asselah T. 2011. J Hepatol, 55: 1150–1153.
        doi: 10.1016/j.jhep.2011.04.025

    5. Feng Y, He D, Yao Z, et al. 2014. Cell Res, 24: 24–41.
        doi: 10.1038/cr.2013.168

    6. Huang H, Kang R, Wang J, et al. 2013. Autophagy, 9: 175–195.
        doi: 10.4161/auto.22791

    7. Li H, Yang X, Yang G, et al. 2014. J Virol, 88: 5956–5966.
        doi: 10.1128/JVI.03738-13

    8. Messina JP, Humphreys I, Flaxman A, et al. 2015. Hepatology, 61: 77–87.
        doi: 10.1002/hep.27259

    9. Moser von Filseck J, Copic A, Delfosse V, et al. 2015. Science, 349: 432–436.
        doi: 10.1126/science.aab1346

    10. Popovic D, Akutsu M, Novak I, et al. 2012. Mol Cell Biol, 32: 1733–1744.
        doi: 10.1128/MCB.06717-11

    11. Seaman MN. 2012. J Cell Sci, 125: 4693–4702.
        doi: 10.1242/jcs.103440

    12. Sica V, Galluzzi L, Bravo-San Pedro JM, et al. 2015. Mol Cell, 59: 522–539.
        doi: 10.1016/j.molcel.2015.07.021

    13. Sir D, Kuo CF, Tian Y, et al. 2012. J Biol Chem, 287: 18036–18043.
        doi: 10.1074/jbc.M111.320085

    14. Yin P, Hong Z, Yang X, et al. 2015. Cell Mol Life Sci, 73:869–881.

  • 加载中

Figures(1)

Article Metrics

Article views(3146) PDF downloads(8) Cited by()

Related
Proportional views
    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Retromer localizes to autophagosomes during HCV replication

      Corresponding author: Leiliang Zhang, armzhang@hotmail.com
      Corresponding author: Youyang Ke, keyouyang001@163.com
    • 1. MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100176, China
    • 2. Department of Emergency, 171st Hospital of PLA, Jiujiang 332000, China

    Abstract: In summary, we propose a model for the role of retromer in HCV replication. Upon HCV infection, retromer may provide double-membrane autophagosomal membranes for HCV replication. Our studies suggested a novel link between retromer and autophagy in HCV replication, which may provide new therapeutic targets for antiviral therapy.