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Citation: Daniel R. Lucey, Kristen R. Kent. Boosting Global Yellow Fever Vaccine Supply for Epidemic Preparedness: 3 Actions for China and the USA [J].VIROLOGICA SINICA, 2019, 34(3) : 235-239.  http://dx.doi.org/10.1007/s12250-019-00129-w

Boosting Global Yellow Fever Vaccine Supply for Epidemic Preparedness: 3 Actions for China and the USA

  • Corresponding author: Daniel R. Lucey, DRL23@georgetown.edu, ORCID: 0000-0002-1027-1926
  • Received Date: 12 February 2019
    Accepted Date: 21 March 2019
    Published Date: 24 May 2019
    Available online: 01 June 2019
  • We advocate for three actions to be taken by the USA and China to help boost global supply of YF vaccine and increase epidemic preparedness and response. First, both nations would work with the WHO to have their YF vaccines prequalified. Thus, their vaccines could be used outside their own borders as part of the international stockpile of YF vaccine as traditionally administrated by the WHO, UNICEF and other members of the multi-partner International Coordinating Group. Second, production of this vaccine would be sharply scaled-up by both countries. These vaccines could be made available nationally, regionally, and globally through the ICG, e.g., to help stop and prevent epidemics anywhere in the world. Third, clinical studies would be coordinated with the WHO to assess the efficacy and safety of fractional dosing using 1/5 normal dose and if needed, even a 1/10 dose.

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    Boosting Global Yellow Fever Vaccine Supply for Epidemic Preparedness: 3 Actions for China and the USA

      Corresponding author: Daniel R. Lucey, DRL23@georgetown.edu
    • 1. Department of Medicine-Infectious Diseases, Georgetown University Hospital, Washington, DC 20057, USA
    • 2. Medical School, Georgetown University School of Medicine, Washington, DC 20057, USA

    Abstract: We advocate for three actions to be taken by the USA and China to help boost global supply of YF vaccine and increase epidemic preparedness and response. First, both nations would work with the WHO to have their YF vaccines prequalified. Thus, their vaccines could be used outside their own borders as part of the international stockpile of YF vaccine as traditionally administrated by the WHO, UNICEF and other members of the multi-partner International Coordinating Group. Second, production of this vaccine would be sharply scaled-up by both countries. These vaccines could be made available nationally, regionally, and globally through the ICG, e.g., to help stop and prevent epidemics anywhere in the world. Third, clinical studies would be coordinated with the WHO to assess the efficacy and safety of fractional dosing using 1/5 normal dose and if needed, even a 1/10 dose.