Citation: Long-ding LIU, Wen-juan WU, Min HONG, Hai-jing SHI, Jing-jing WANG, Hong-ling ZHAO, Yun LIAO, Qi-han LI. Phylogenetic Analysis of Homologous Proteins Encoded by UL2 and UL23 genes of Herpesviridae .VIROLOGICA SINICA, 2007, 22(3) : 207-211.

Phylogenetic Analysis of Homologous Proteins Encoded by UL2 and UL23 genes of Herpesviridae

  • Corresponding author: Qi-han LI, qihanli@21cn.com
  • Received Date: 26 October 2006
    Accepted Date: 20 February 2007
    Available online: 01 June 2007

    Fund Project: National Natural Science Funds 30570081

  • The proteins encoded by the Herpesviridae -gene play a critical role in the replication stage of the virus. In this paper, phylogenetic analyses provided evidence that some -gene products, such as UL2 and UL23 from HSV1, have their homologous genes in its family, and also exist in prokaryotic organisms, indicating that these viruses appear to have been assembled over evolutionary time by numerous independent events of horizontal gene transfer.

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    1. AIba M M, Das R, Orengo C A, et al. 2001. Genomewide function conservation and phylogeny in the Herpesviridae. Genome Res, 11 (1): 43-54.
        doi: 10.1101/gr.149801

    2. Chen F, Suttle C A. 1996. Evolutionary relationships among large double-stranded DNA viruses that infect microalgae and other organisms as inferred from DNA polymerase genes. Virology, 219: 170-178.
        doi: 10.1006/viro.1996.0234

    3. Davison A J. 2002. Evolution of the herpesviruses. Vet Microbiol, 86 (1-2): 69-88.
        doi: 10.1016/S0378-1135(01)00492-8

    4. Davison A J, Dargan D J, Stow N D. 2002. Fundamental and accessory systems in herpesviruses. Antiviral Res, 56 (1): 1-11.
        doi: 10.1016/S0166-3542(02)00107-9

    5. Deregt D, Gilbert S A, Campbell I. 2005. Phylogeny and antigenic relationships of three cervid herpesviruses. Virus Res, 114: 140-148.
        doi: 10.1016/j.virusres.2005.06.007

    6. Fang Q, Liu J, Bai Z Q, et al. 2006. Seroprevalence of Kaposi's Sarcoma-associated Herpesvirus in the General Population from Hubei Province. Virologica sinica, 21: 97-101.

    7. Gerner C S, Dolan A, McGeoch D J. 2004. Phylogenetic relationships in the Lymphocryptovirus genus of the Gammaherpesvirinae. Virus Res, 99 (2): 187-192.
        doi: 10.1016/j.virusres.2003.10.011

    8. Kajumbula H, Wallace R G, Zong J C, et al. 2006.Ugandan Kaposi's sarcoma-associated herpesvirus phylogeny: evidence for cross-ethnic transmission of viral subtypes. Intervirology, 49 (3): 133-143.
        doi: 10.1159/000089374

    9. Karlin S, Mocarski E S, Schachtel G A. 1994. Molecular evolution of herpesviruses: genomic and protein sequence comparisons. J Virol, 68 (3): 1886-1902.

    10. Kumar S, Tamura K, Nei M. 2004. MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform, 5 (2): 150-163.
        doi: 10.1093/bib/5.2.150

    11. McGeoch D J. 2001. Molecular evolution of the gamma-Herpesvirinae. Philos Trans R Soc Lond B Biol Sci, 356 (1408): 421-435.
        doi: 10.1098/rstb.2000.0775

    12. McGeoch D J, Cook S. 1994. Molecular phylogeny of the alphaherpesvirinae subfamily and a proposed evolutionary timescale.. J Mol Biol, 238: 9-22.
        doi: 10.1006/jmbi.1994.1264

    13. McGeoch D J, Cook S, Dolan A, et al. 1995. Molecular phylogeny and evolutionary timescale for the family of mammalian herpesviruses. J Mol Biol, 247 (3): 443-458.
        doi: 10.1006/jmbi.1995.0152

    14. McGeoch D J, Rixon F J, Davison A J. 2006. Topics in herpesvirus genomics and evolution. Virus Res, 117 (1): 90-104.
        doi: 10.1016/j.virusres.2006.01.002

    15. Montague M G, Hutchison C A, 3rd. 2000. Gene content phylogeny of herpesviruses. Proc Natl Acad Sci USA, 97 (10): 5334-5339.
        doi: 10.1073/pnas.97.10.5334

    16. Norberg P, Bergstrom T, Rekabdar E, et al. 2004. Phylogenetic analysis of clinical herpes simplex virus type 1 isolates identified three genetic groups and recombinant viruses [J]. J Virol, 78 (19): 10755-10764.
        doi: 10.1128/JVI.78.19.10755-10764.2004

    17. Ros C, Belak S. 1999. Studies of genetic relationships between bovine, caprine, cervine, and rangiferine alphaherpesviruses and improved molecular methods for virus detection and identification. J Clin Microbiol, 37 (5): 1247-1253.

    18. Willoughby K, Bennett M, McCracken C M, et al. 1999. Molecular phylogenetic analysis of felid herpesvirus 1. Vet Microbiol, 69 (1-2): 93-97.
        doi: 10.1016/S0378-1135(99)00094-2

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    Phylogenetic Analysis of Homologous Proteins Encoded by UL2 and UL23 genes of Herpesviridae

      Corresponding author: Qi-han LI, qihanli@21cn.com
    • Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming 650118, China
    Fund Project:  National Natural Science Funds 30570081

    Abstract: The proteins encoded by the Herpesviridae -gene play a critical role in the replication stage of the virus. In this paper, phylogenetic analyses provided evidence that some -gene products, such as UL2 and UL23 from HSV1, have their homologous genes in its family, and also exist in prokaryotic organisms, indicating that these viruses appear to have been assembled over evolutionary time by numerous independent events of horizontal gene transfer.