>> May Vol. 31, No 3, 2016
Virologica Sinica publishes peer-reviewed original research articles and reviews concerning the latest developments in all branches of virology, including the research on the viruses of animals, plants and microbes. The journal welcomes studies on viruses as well as on viral infections and diseases. The journal will feature articles on new virus discovery, molecular characterization of viruses, viral pathogenesis and host immunity, vaccine development, antiviral ...   (read more)
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Official journal of the Chinese Society for Microbiology
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ISSN: 1674-0769
EISSN: 1995-820X
CN: 42-1760/Q
Perspective
Giant viruses from the Mimiviridae family (Mimivirus, Megavirus, etc.) replicate inside their Acanthamoeba host by the mean of a large intracytoplasmic virion factory within which DNA transcription and replication take place using the virus encoded machineries. Members of the Mimiviridae have been ..., Abstract
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Perspective
The International Committee on Taxonomy of Viruses (ICTV) has the decree to set the rules for the classification and naming of viruses. The species is the lowest level considered in the taxonomic hierarchy. In general, virus species are named according to the structure “ ..., Abstract
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Research Article
The multifunctional trans-activator Tat is an essential regulatory protein for HIV-1 replication and is characterized by high sequence diversity. Numerous experimental studies have examined Tat in HIV-1 subtype B, but research on subtype C Tat is lacking, despite the high prevalence ..., Abstract
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Research Article
A transmission bottleneck occurs during each human immunodeficiency virus (HIV) transmission event, which allows only a few viruses to establish new infection. However, the genetic characteristics of the transmitted viruses that are preferentially selected have not been fully elucidated. Here ..., Abstract
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Research Article
Congenital human cytomegalovirus (HCMV) infection is a leading infectious cause of birth defects. Previous studies have reported birth defects with multiple organ maldevelopment in congenital HCMV-infected neonates. Multipotent mesenchymal stromal cells (MSCs) are a group of stem/progenitor ..., Abstract
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Research Article
Within Baculoviridae, little is known about the molecular mechanisms of replication in betabaculoviruses, despite extensive studies in alphabaculoviruses. In this study, the promoters of nine late genes of the betabaculovirus Plutella xylostella granulovirus (PlxyGV) were cloned into a transient ..., Abstract
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Research Article
Fibroblast growth factor (FGF) is found throughout multicellular organisms; however, fgf homologs (vfgf) have only been identified among viruses in lepidopteran baculoviruses. The function of vFGFs from Group I alphabaculoviruses, including Autographa californica multiple ..., Abstract
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Research Article
Foot-and-mouth disease virus (FMDV) is the causative agent of a highly contagious disease in livestock. The viral proteinase Lpro of FMDV is involved in pathogenicity, and mutation of the Lpro SAP domain reduces FMDV pathogenicity in pigs. To determine the gene expression ..., Abstract
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Letter
Astrovirus is an enteric virus associated with sporadic diarrhea or large outbreaks of gastroenteritis (Mendez et al., 2013). Until 2008, human astroviruses (HAstVs) were classified into eight serotypes—HAstV-1 to HAstV- 8—based on the reactivity of their capsid protein with type-specific ..., Abstract
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Letter
Since April 2010, an outbreak of a new disease has elicited symptoms of high fever, loss of appetite, and reduction in egg production in layer ducks in eastern China; this phenomenon has now spread throughout China (Cao et al., 2011; Su et al., 2011). The causative agent of the disease was ..., Abstract
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Letter
Infectious bursal disease virus (IBDV) causes infectious bursal disease, a highly contagious immunosuppressive disease that affects young chickens and causes economic losses in the poultry industry worldwide. IBDV replicates mainly in actively dividing B lymphocytes within the bursa of ..., Abstract
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Letter
The Poxviridae family is divided into Chordopoxvirinae and Entomopoxvirinae genera. Parapoxvirus is one of 11 genera in the Chordopoxvirinae genus, including orf virus (ORFV), bovine papular stomatitis virus (BPSV), pseudocowpox virus (PCPV) and parapoxvirus of red deer in New Zealand (PVNZ) ..., Abstract
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Letter
Akabane virus (AKAV), an orthobunyavirus, is transmitted primarily by biting midges and is widely distributed throughout the world except the Europe. AKAV was first isolated from mosquitoes in Japan (Oya et al., 1961). Although pregnant cows, ewes, and goats infected with AKAV exhibit no ..., Abstract
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