>> September Vol. 31, No 5, 2016
Virologica Sinica publishes peer-reviewed original research articles and reviews concerning the latest developments in all branches of virology, including the research on the viruses of animals, plants and microbes. The journal welcomes studies on viruses as well as on viral infections and diseases. The journal will feature articles on new virus discovery, molecular characterization of viruses, viral pathogenesis and host immunity, vaccine development, antiviral ...   (read more)
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Official journal of the Chinese Society for Microbiology
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ISSN: 1674-0769
EISSN: 1995-820X
CN: 42-1760/Q
Three-dimensional (3D) culture models are physiologically relevant, as they provide reproducible results, experimental flexibility and can be adapted for high-throughput experiments. Moreover, these models bridge the gap between traditional two-dimensional (2D) monolayer cultures and animal ..., Abstract
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Mammarenaviruses, including lethal pathogens such as Lassa virus and Junín virus, can cause severe hemorrhagic fever in humans. Entry is a key step for virus infection, which starts with binding of the envelope glycoprotein (GP) to receptors on target cells and subsequent fusion of the virus ..., Abstract
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The cell membrane regulates many physiological processes including cellular communication, homing and metabolism. It is therefore not surprising that the composition of the host cell membrane is manipulated by intracellular pathogens. Among these, the human oncogenic herpesviruses Epstein–Barr ..., Abstract
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Research Article
Ficolin-2 is a lectin complement pathway activator present in normal human plasma and usually associated with infectious diseases, but little is known about the role of ficolin-2 in human immunodeficiency virus (HIV) infection. Here, we describe our novel findings that serum ficolin-2 ..., Abstract
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Research Article
Human immunodeficiency virus-1 (HIV-1) encodes 15 viral proteins. Protein-protein interactions play a large role in the function of these proteins. In this study, we attempted to identify novel interactions between the HIV-1 proteins to better understand the role played by viral protein-protein ..., Abstract
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Research Article
Cells of the P8-Se301-C1 strain are Spodoptera exigua cell clones that each harbor a partial version of the S. exigua multiple nucleopolyhedrovirus (SeMNPV) genome and which are resistant to homologous SeMNPV infections. The cells produce no viral progeny, suggesting that the infection is ..., Abstract
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Human papillomaviruses (HPV) are a large group (> 200 genotypes) of small double-stranded DNA viruses (https://pave.niaid.nih.gov/). Although infections by most HPV types are asymptomatic, persistent infections in cervical and ano-genital epithelia by high-risk HPV can lead to the development ..., Abstract
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The influenza viruses cause continual epidemics in human society. As is reported by the World Health Organization (WHO), each year the seasonal influenza viruses, i.e., human influenza A (H1N1), A (H3N2) and B viruses, infected 5%~15% of the world’s population, leading to about 3 to 5 million ..., Abstract
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Influenza A viruses (IAVs) are single-stranded, negative sense RNA viruses. IAV subtype is determined on the basis of the viral surface glycoproteins, hemagglutinin (HA), and neuraminidase (NA). To date, 18 HA and 11 NA subtypes have been reported (Tong et al., 2012). IAVs can cause sporadic ..., Abstract
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Restriction endonuclease analysis (REA), or restriction fragment length polymorphism (RFLP), was useful for identifying and determining the relatedness and putative identities of microbial strains (Tang et al., 1997) and for characterizing and discriminating large numbers of samples ..., Abstract
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Several recent studies in Virologica Sinica and other journals have highlighted the enormous international challenge of emerging arboviral diseases, such as Zika virus disease, dengue, and chikungunya (Islam et al., 2015; Maurice et al., 2015; Dai et al., 2016; Deng et al., 2016; ..., Abstract
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