The Establishment and Validation of the Human U937 Cell Line as a Cellular Model to Screen Immunomodulatory Agents Regulating Cytokine Release Induced by Influenza Virus Infection

Ge Liu; Si Chen; Ao Hu; Li Zhang; Wenyu Sun; Jungang Chen; Wei Tang; Haiwei Zhang; Chunlan Liu; Chang Ke; Xulin Chen

doi:10.1007/s12250-019-00145-w

December 2019

Citation: Ge Liu, Si Chen, Ao Hu, Li Zhang, Wenyu Sun, Jungang Chen, Wei Tang, Haiwei Zhang, Chunlan Liu, Chang Ke, Xulin Chen. The Establishment and Validation of the Human U937 Cell Line as a Cellular Model to Screen Immunomodulatory Agents Regulating Cytokine Release Induced by Influenza Virus Infection .VIROLOGICA SINICA, 2019, 34(6) : 648-661. http://dx.doi.org/10.1007/s12250-019-00145-w

The Establishment and Validation of the Human U937 Cell Line as a Cellular Model to Screen Immunomodulatory Agents Regulating Cytokine Release Induced by Influenza Virus Infection

Ge Liu ^1,2 ,
Si Chen ^1,2 ,
Ao Hu ^1,2 ,
Li Zhang ^1,2 ,
Wenyu Sun ^1,2 ,
Jungang Chen ¹ ,
Wei Tang ¹ ,
Haiwei Zhang ¹ ,
Chunlan Liu ¹ ,
Chang Ke ³ ,
Xulin Chen ^{1,2
,,}

1.
State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China
2.
University of Chinese Academy of Sciences, Beijing 100049, China
3.
Wuhan Virolead Biopharmaceutical Company, Wuhan 430075, China

Corresponding author: Xulin Chen, chenxl@wh.iov.cn, ORCID: http://orcid.org/0000-0002-4479-1145