Identification and genome characterization of circovirus in masked palm civets (<em>Paguma larvata</em>) from Guangdong Province, China

Pian Zhang; Jing Chen; Xiaofan Chen; Chenglong Sun; Zhaowen Ren; Yin Mei; Fumin Wang; Xiaoxiao Zhang; Yangrui Lu; Xu Wang; Hua Xiang; Yuan Huang; Gang Wang; Ming Liao; Xiaohu Wang

doi:10.1016/j.virs.2026.09.001

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Volume 41 Issue 5

October 2026

Citation: Pian Zhang, Jing Chen, Xiaofan Chen, Chenglong Sun, Zhaowen Ren, Yin Mei, Fumin Wang, Xiaoxiao Zhang, Yangrui Lu, Xu Wang, Hua Xiang, Yuan Huang, Gang Wang, Ming Liao, Xiaohu Wang. Identification and genome characterization of circovirus in masked palm civets (Paguma larvata) from Guangdong Province, China .VIROLOGICA SINICA, 2026, 41(5) : 1247-1250. http://dx.doi.org/10.1016/j.virs.2026.09.001

Identification and genome characterization of circovirus in masked palm civets (Paguma larvata) from Guangdong Province, China

Pian Zhang ^a ,
Jing Chen ^a ,
Xiaofan Chen ^a ,
Chenglong Sun ^b ,
Zhaowen Ren ^a ,
Yin Mei ^c ,
Fumin Wang ^c ,
Xiaoxiao Zhang ^a ,
Yangrui Lu ^a ,
Xu Wang ^a,d ,
Hua Xiang ^a ,
Yuan Huang ^a ,
Gang Wang ^{a
,,} ,
Ming Liao ^{a,d
,,} ,
Xiaohu Wang ^{a
,,}

a. Guangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
b. Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA;
c. Guangdong Provincial Wildlife Monitoring and Rescue Center, Guangzhou 510000, China;
d. College of Animal Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China

Corresponding author: Gang Wang, wanggang@gdaas.cn
Ming Liao, mliao@scau.edu.cn
Xiaohu Wang, wangxiaohu2020@163.com
Received Date: 27 March 2026
Accepted Date: 01 September 2026
Available online: 03 September 2026

Abstract

Highlights
1 First identification of Pl-CV in Chinese mainland, with a 34.0% detection rate in farmed civets.
2 Pl-CV DNA was detected in liver (31.4%) and intestine (25.7%) specimens from one Shaoguan farm.
3 Four complete genomes show 87.4%–90.0% nucleotide identity with Japanese civet circoviruses.

Electronic Supplementary Material

10.1016j.virs.2026.09.001-ESM.docx
References
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2. Chen, S., Li, W., Fan, L., Xu, C., Liu, S., Li, H., Liu, P., Zhu, W., Wu, X., Qin, P., Li, J., Ma, X., Wei, Y., 2026. Metatranscriptomics profiling reveals rodent- and shrew-borne viral diversity and evolutionary relationships in Guangzhou, China. Virol. Sin. 41, 35-47.
3. Dai, Z., Wang, H., Feng, Z., Ma, L., Yang, S., Shen, Q., Wang, X., Zhou, T., Zhang, W., 2021. Identification of a novel circovirus in blood sample of giant pandas (Ailuropoda melanoleuca). Infect. Genet. Evol. 95, 105077.
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Identification and genome characterization of circovirus in masked palm civets (Paguma larvata) from Guangdong Province, China

Corresponding author: Gang Wang, wanggang@gdaas.cn

Corresponding author: Ming Liao, mliao@scau.edu.cn

Corresponding author: Xiaohu Wang, wangxiaohu2020@163.com

a. Guangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
b. Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA;
c. Guangdong Provincial Wildlife Monitoring and Rescue Center, Guangzhou 510000, China;
d. College of Animal Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China

Received Date: 27 March 2026
Accepted Date: 01 September 2026

Abstract: Highlights
1 First identification of Pl-CV in Chinese mainland, with a 34.0% detection rate in farmed civets.
2 Pl-CV DNA was detected in liver (31.4%) and intestine (25.7%) specimens from one Shaoguan farm.
3 Four complete genomes show 87.4%–90.0% nucleotide identity with Japanese civet circoviruses.