Study of Effect of EHFV on Peripheral Blood Lymphocytes of Healthy Persons in Vitro and on Bone Marrow Cells of Rats in Vivo
Abstract: Epidemic hemorrhagic fever virus(EHFV) A9 strain was inoculated into peripheral blood samples of 10 normal persons for incubation and sister chromatid exchange (SCE) and chromosome abnormality of lymphocytes were examined, Three experimental groups, named A, B, and C according to different dosages of virus supernatant and one group without virus as control were used. The frequencies of SCE of group A(8.9±0.19), of group B(9.9±0.2), of group C(11.6±0.12) were each significantly higher than that of control gr...