Citation: FANG De-Xin, GAN Ren-Bao, LI Zai-Beng, DI Chun-Sheng, ZHOU Zong-An. Different Nueleotide Sequences within One of Hepatitis B Virus Clones Patient .VIROLOGICA SINICA, 1999, 14(1) : 52-57.

Different Nueleotide Sequences within One of Hepatitis B Virus Clones Patient

  • Available online: 05 March 1999
  • The HBV HBsAg coding region of a hepatitis B patient was analyzed by PCR amplification, bacteriophage cloning and nucleotide sequencing. It was showed that among different clones from the same patient there were point mutations and these different nucleotide changes were not resulted from the methodologies. It is concluded that there are polymorphic HBV genomes within the same hepatitis B patient

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    Different Nueleotide Sequences within One of Hepatitis B Virus Clones Patient

    • 1. Huadong Research Institute for Medical Biotechnics,Nanfing 210002

    Abstract: The HBV HBsAg coding region of a hepatitis B patient was analyzed by PCR amplification, bacteriophage cloning and nucleotide sequencing. It was showed that among different clones from the same patient there were point mutations and these different nucleotide changes were not resulted from the methodologies. It is concluded that there are polymorphic HBV genomes within the same hepatitis B patient

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