LI Xiang—jun, REN Li—qun “, LI Guang—sheng, WAN Min.The RelatiOnship Between the Geonome and Its Variation of Coxasckievirus B3 and Myocardium Inj ury .VIROLOGICA SINICA, 2002, 17(3): 286-288.
Citation:
LI Xiang—jun, REN Li—qun “, LI Guang—sheng, WAN Min.
The RelatiOnship Between the Geonome and Its Variation of Coxasckievirus B3 and Myocardium Inj ury .VIROLOGICA SINICA, 2002, 17(3)
: 286-288.
The RelatiOnship Between the Geonome and Its Variation of Coxasckievirus B3 and Myocardium Inj ury
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1.Institute of Biological Engineering,Norman Bethune department ofMedical Science,Jilin University,Changchun 130021, China
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partment of Biomolecular Laboratory,School of BⅡs Medical&iences,Jilin University, Changchun 130021,China
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Available online:
05 June 2002
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Abstract
肠道病毒感染是人类急性和慢性心肌炎的常见 病因之一,而且也与人类扩张型心肌病(DCM)的发 生发展有密切关系⋯ 。病毒分离,血清学研究,免 疫组化技术、原位核酸杂交技术以及聚合酶链反应 技术(PCR)均提示肠道病毒与心肌炎关系密切。最 近,LI等[ ]用肠道病毒特异性单克隆抗体,采用改 良的免疫组化技术对心肌炎或DCM 病人心肌切片 中肠道病毒抗原进行检测,此法直接证明了心肌炎 或DCM 病人体内确实有子代病毒产生。但是,肠 道病毒究竟通过怎样的机制引起心肌损伤还未阐 明,推测可能有多种机制参与。本文仅就肠道病毒 (柯萨奇病毒B3,CVB3)基因组结构及其基因变异 与心肌损伤的关系方面加以综述。
Keywords:
- 柯萨奇病毒B3
- , 基因组
- , 心肌损伤
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References
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Proportional views
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