Genome Comparison Between SARS—associated coronavirus andOther Coronaviruses
Abstract: Abstract:The genome sequences of SARS.associated coronavirus (SARS.COV)were compared witIlother Coronaviruses.Similar sequences were found by searching biomolecular databases.Sequenceanalysis showed that SARS.CoV had similar genomi c organization and structural proteins whilecompared with other Coronaviruses.SARS.CoV is related to other known Coronaviruses.But therewere some specific sequences in SARS.CoV genome.Th e virulence of SARS may deftve fromvaxi~ions of ORF l a an d S protein an d the specificity of some nonstructural proteins.Th e result of wordfrequency an alysis indicated that SARS.CoV does not closely resemble an y of kn own Coronaviruses.