An Anti-species-sharing-idiotypic Antibody to AIV Bearing the Internal Image of Hemagglutinin on AIV
Abstract: One anti-idiotypic monoclonal antibody（a-Id Mab）was raised directed to both rabbit and chicken IgG against Avian influenza virus(AIV). The Mab was able to inhibit the binding of AIV to anti-AIV IgG and specific in binding anti-H9-subtype-AIV IgG. Another experiment demonstrated that the Mab might induce chicken to generate hemagglutination inhibition antibodies. These results indicated this anti-species-sharing-idiotypic antibody bore the internal image of hemagglutinin on AIV.