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Citation: Congcong Wang, Huanhuan Feng, Xiangle Zhang, Kangli Li, Fan Yang, Weijun Cao, Huisheng Liu, Lili Gao, Zhaoning Xue, Xiangtao Liu, Zixiang Zhu, Haixue Zheng. Correction to: Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function [J].VIROLOGICA SINICA, 2021, 36(6) : 1688-1689.  http://dx.doi.org/10.1007/s12250-021-00466-9

Correction to: Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function

  • Corresponding author: Zixiang Zhu, zhuzixiang@126.com, ORCID: 0000-0002-4093-9683
    Haixue Zheng, haixuezheng@163.com, ORCID: 0000-0001-6143-6850
  • Published Date: 12 November 2021
    Available online: 01 December 2021

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    Correction to: Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function

      Corresponding author: Zixiang Zhu, zhuzixiang@126.com
      Corresponding author: Haixue Zheng, haixuezheng@163.com
    • 1. State Key Laboratory of Veterinary Etiological Biology, OIE/ National Foot and Mouth Diseases Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China

    Abstract: 

    • Correction to: Virologica Sinica (2021) 36:948–957

      https://doi.org/10.1007/s12250-021-00352-4

      Due to our negligence, the original version of this article, published online on March 15, 2021, contained a mistake in Figure 2E (The Knockdown band of Western blotting was provided incorrectly). The correct Fig. 2E is given below. We apologize for this error and state that this does not change the scientific conclusions of the article in any way.

      Figure 2.  PRDX6 inhibited FMDV replication. A–C PK-15 cells were transfected with 0, 0.5, 1 or 2 μg of Myc-PRDX6 expressing plasmids for 24 h. The cells were then infected with FMDV (MOI = 0.5) for 12 h. The expression of viral proteins (A) and viral RNA (B) were detected by Western blotting and qPCR respectively. The virus yields were measured by TCID50 assay (C). D EC-4 cells were transfected with 0, 1 or 2 μg of Myc-PRDX6 expressing plasmids for 24 h. The cells were then mock-infected or infected with FMDV for 12 h. The expression of viral proteins and viral RNA were detected by Western blotting and qPCR respectively. E PK-15 cells were transfected with 120 nM of nontargeting control NC siRNA or PRDX6 siRNA (siRNA-329, siRNA-645 siRNA-729) for 36 h, the knockdown efficiency of each siRNA was then evaluated by qPCR and Western blotting analysis respectively. F–H PK-15 cells were transfected with 120 nM of NC siRNA or PRDX6 siRNA (siRNA-329) for 36 h, the cells were then infected with FMDV (MOI = 0.5) for 0, 4, 8 or 12 h. The expression of viral proteins (F) and viral RNA (G) were detected by Western blotting and qPCR respectively. The virus yields were measured by TCID50 assay (H).

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