Citation: WANG Jian-Ling, YAN Yong-Jie. POTENTIATION OF INTERFERON S ANTIVIRAL ACTIVITY BY COMBINED PREPARATIONS OF HUMAN ALPHA AND GAMMA INTERFERONS .VIROLOGICA SINICA, 1987, 2(3) : 50.

POTENTIATION OF INTERFERON S ANTIVIRAL ACTIVITY BY COMBINED PREPARATIONS OF HUMAN ALPHA AND GAMMA INTERFERONS

  • Available online: 05 September 1987
  • Potentiation of interferon s antiviral activity was determined by replication inhibition of vesicular stomatitis virus in human lung cancer calls(A549). Combined preparations of human IFN-α and IFN-γ interacted with cells synergistically to cause a much grearer level of protection than that expected on the basis of their additive or multiplicative effect. The potentiation was not the artifact of an accelerated development of IFN-γ-induced antiviral resistance in the presence of IFN-α. The rest components in...

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    POTENTIATION OF INTERFERON S ANTIVIRAL ACTIVITY BY COMBINED PREPARATIONS OF HUMAN ALPHA AND GAMMA INTERFERONS

    • 1. Department of Microbiology
    • 2. Nanjing College of Chinese Traditional Medicine: NanjingSun Yatsen University of Medical Sciences

    Abstract: Potentiation of interferon s antiviral activity was determined by replication inhibition of vesicular stomatitis virus in human lung cancer calls(A549). Combined preparations of human IFN-α and IFN-γ interacted with cells synergistically to cause a much grearer level of protection than that expected on the basis of their additive or multiplicative effect. The potentiation was not the artifact of an accelerated development of IFN-γ-induced antiviral resistance in the presence of IFN-α. The rest components in...

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