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Volume 07 Issue 1
February 1992
    Citation: LI Qi-Han, DAI Chang-Bai, YUAN Tian-Xi, HU Ning-Zhu, SU Ye, GUO Ren, HOU Yun-De, DAO Ying-Shuang. The Function of Poliovirus 2A Proteinase in the Polio-Vaccinia Recombinant Virus .VIROLOGICA SINICA, 1992, 7(1) : 43.
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    The Function of Poliovirus 2A Proteinase in the Polio-Vaccinia Recombinant Virus

    • 1.

      Institute of Medical Biology

    • 2.

      Chinese Academy of Medical Sciences

    • 3.

      Kunming 650107

    • Available online: 05 March 1992
    • For studying the function of Poliovirus 2A proteinaes in Polio-Vaccinarecombinant virus, We constructed the various chimeric virus of Polio-Vac-cinia, and obtained 4 Polio--Vaccinia recombinant viruses which contain var-ious fragments of Polio virus I type mahoney strain gene. These fragmentswere inserted into the TK region of vaccinia gene. The antigen of Polioviruswas expressed in these 4 recombinant viruses, the antibody against Poliovirusl type was induced in the rabbit infected by these chimeric viruse...
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      The Function of Poliovirus 2A Proteinase in the Polio-Vaccinia Recombinant Virus

      • 1. Institute of Medical Biology
      • 2. Chinese Academy of Medical Sciences
      • 3. Kunming 650107

      Abstract: For studying the function of Poliovirus 2A proteinaes in Polio-Vaccinarecombinant virus, We constructed the various chimeric virus of Polio-Vac-cinia, and obtained 4 Polio--Vaccinia recombinant viruses which contain var-ious fragments of Polio virus I type mahoney strain gene. These fragmentswere inserted into the TK region of vaccinia gene. The antigen of Polioviruswas expressed in these 4 recombinant viruses, the antibody against Poliovirusl type was induced in the rabbit infected by these chimeric viruse...

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