The Cooperative Anti-influenza Virus Activities of Amantadine, Ribavirin and Herby Houttuynia
Abstract: The research Of the cooperative antivirus activities was carried OUt using anaantadine. rib— avirin and herhy houttuynia.The inhibitory effect 0f CPE caused by influenza virus A3 in MDCK cd and the therapeutic effect on BALB/c mice pneumonia caused by influenza virus FM1 were examined and analyzed when amantadine,ribavirin and herby houttuynia were used alone or assoeiatively The results show that the concentrations Of amantadine,ribavirin and herby houttuynia with sanle effeet were 256,512 and 1024 times cooperatively as many as alone in vitro,respectively.The ablities of treating pneumonia of mice when three kinds of drugs were used coperatively were far higher than those alone in BAI B/c mice